乙基L-天冬氨酰胺酸酯盐酸盐(1:1) | 24184-37-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 乙基L-天冬氨酰胺酸酯盐酸盐(1:1)
• 中文别名: 乙基L-天冬酰胺酸酯盐酸盐
• 英文名称: L-asparagine ethyl ester hydrochloride
• 英文别名: asparagine ethyl ester hydrochloride；Ethyl L-asparaginate monohydrochloride；ethyl (2S)-2,4-diamino-4-oxobutanoate;hydrochloride
• CAS: 24184-37-0
• 化学式: C₆H₁₂N₂O₃*ClH
• 分子量: 196.634
• InChiKey: RIGBOVZPZYVXER-WCCKRBBISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.83
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  95.4
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  乙基L-天冬氨酰胺酸酯盐酸盐(1:1) 、 溴代十二烷 在 碳酸氢钠 作用下， 以 乙腈 为溶剂， 反应 18.0h， 生成
  参考文献：
  名称：

  Thermodynamic, kinetic and mechanistic approach to the corrosion inhibition of carbon steel by new synthesized amino acids-based surfactants as green inhibitors in neutral and alkaline aqueous media

  摘要：

  The inhibiting power of three synthesized amino acids based-surfactant molecules, namely, sodium N-dodecyl asparagines (AS), sodium N-dodecylhistidine (HS) and sodium N-dodecyltryptophan (TS) on the dissolution of carbon steel was inspected in 0.5 M NaCI and 05 M NaOH solutions at 25 degrees C. The methods employed in this work were weight-loss (WL), potentiodynamic polarization (PP) and electrochemical impedance spectroscopy (EIS). The chemical structures of the synthesized surfactants were confirmed by FT-IR and (HNMR)-H-1. The inhibition efficiencies were found to increase as the surfactants concentrations increase, while decreasing with increasing the concentration of the corrosive media (NaCI & NaOH) and temperature. Results obtained from the different techniques revealed that the inhibition efficiency of the compound TS was higher than those of both AS and HS. The inhibition efficiencies of the synthesized surfactants were declined in terms of strong adsorption of surfactants on the surface of carbon steel and forming a protective film and such adsorption was found to obey Langmuir isotherm. Both thermodynamic and kinetic parameters were evaluated which support the mechanism of physical adsorption of the inhibitors. The tested surfactants were found to act as mixed-type inhibitors with anodic predominance. The surface morphology of the carbon steel surface was examined by scanning electron microscopy (SEM). The inhibitory mechanism of carbon steel corrosion was suggested. Results obtained from all employed methods are consistent with each other. (C) 2018 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molliq.2018.05.140
• 作为产物：
  描述：

  乙醇 、 L-天冬酰胺 在 氯化亚砜 作用下， 反应 16.0h， 生成 乙基L-天冬氨酰胺酸酯盐酸盐(1:1)
  参考文献：
  名称：

  Thermodynamic, kinetic and mechanistic approach to the corrosion inhibition of carbon steel by new synthesized amino acids-based surfactants as green inhibitors in neutral and alkaline aqueous media

  摘要：

  The inhibiting power of three synthesized amino acids based-surfactant molecules, namely, sodium N-dodecyl asparagines (AS), sodium N-dodecylhistidine (HS) and sodium N-dodecyltryptophan (TS) on the dissolution of carbon steel was inspected in 0.5 M NaCI and 05 M NaOH solutions at 25 degrees C. The methods employed in this work were weight-loss (WL), potentiodynamic polarization (PP) and electrochemical impedance spectroscopy (EIS). The chemical structures of the synthesized surfactants were confirmed by FT-IR and (HNMR)-H-1. The inhibition efficiencies were found to increase as the surfactants concentrations increase, while decreasing with increasing the concentration of the corrosive media (NaCI & NaOH) and temperature. Results obtained from the different techniques revealed that the inhibition efficiency of the compound TS was higher than those of both AS and HS. The inhibition efficiencies of the synthesized surfactants were declined in terms of strong adsorption of surfactants on the surface of carbon steel and forming a protective film and such adsorption was found to obey Langmuir isotherm. Both thermodynamic and kinetic parameters were evaluated which support the mechanism of physical adsorption of the inhibitors. The tested surfactants were found to act as mixed-type inhibitors with anodic predominance. The surface morphology of the carbon steel surface was examined by scanning electron microscopy (SEM). The inhibitory mechanism of carbon steel corrosion was suggested. Results obtained from all employed methods are consistent with each other. (C) 2018 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molliq.2018.05.140

文献信息

• [EN] BETA-HYDROXYBUTYRYL-AMINO ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF<br/>[FR] COMPOSÉ D'ACIDE BÊTA-HYDROXYBUTYRYL-AMINÉ, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION<br/>[ZH] 一种β-羟基丁酰-氨基酸化合物及制备方法和应用
  申请人：LIU CHENG

  公开号：WO2019104851A4

  公开（公告）日：2019-08-15

  [EN] Beta-hydroxybutyryl-amino acid compounds represented by formulas I, II, III, IV, V, VI, VII, VIII, IX and X, a preparation method therefor and use thereof. The compounds have antitumor activity and can be used for weight loss, anti-aging, treatment of Alzheimer's disease and epilepsy, lowering blood lipids, and lowering blood pressure.
  [FR] La présente invention concerne des composés d'acide bêta-hydroxybutyryl-aminé représentés par les formules I, II, III, IV, V, VI, VII, VIII, IX et X, leur procédé de préparation et leur utilisation. Les composés ont une activité antitumorale et peuvent être utilisés pour la perte de poids, comme anti-âge, pour le traitement de la maladie d'Alzheimer et l'épilepsie, pour la réduction des lipides dans le sang et pour la diminution de la pression artérielle.
  [ZH] 式I、Ⅱ、Ⅲ、Ⅳ、Ⅴ、Ⅵ、Ⅶ、Ⅷ、Ⅸ、Ⅹ所示的β-羟基丁酰-氨基酸化合物及制备方法和应用，所述化合物具有抑癌活性并可用于减肥、抗衰老、治疗阿尔海默症和癫痫、降血脂、降血压。