2-[(1-cyclohexenyl)methyl]-2-phenyl-1,3-indandione

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 2-[(1-cyclohexenyl)methyl]-2-phenyl-1,3-indandione
• 英文别名: 2-(Cyclohexen-1-ylmethyl)-2-phenylindene-1,3-dione
• 化学式: C₂₂H₂₀O₂
• 分子量: 316.4
• InChiKey: PSEUESQNSPKCKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (cyclohexylidenemethyl)trimethylsilane 在 三氟化硼乙醚 、 potassium tert-butylate 、 N,N-二异丙基乙胺 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 41.5h， 生成 2-[(1-cyclohexenyl)methyl]-2-phenyl-1,3-indandione
  参考文献：
  名称：

  Onium Transfer Reaction of (β,β-Dialkylvinyl)(phenyl)iodonium Tetrafluoroborates via an Alkylidene Carbene Pathway:  Synthesis of Group 15 Alkenyl(triphenyl)- and Group 16 Alkenyl(diphenyl)onium Salts

  摘要：

  Group 15 1-alkenyl(triphenyl)onium (P, As, Sb) tetrafluoroborates were prepared via an onium transfer reaction of alkenyl(phenyl)iodonium tetrafluoroborates under mild conditions. The reaction involves base-induced reductive alpha-elimination of the iodonium salts, followed by nucleophilic trapping of the resulting free alkylidene carbenes with group 15 element-centered nucleophiles. The onium transfer reaction of the alkenyliodonium salts also produced group 16 1-alkenyl(diphenyl)onium (S, Se, Te) tetrafluoroborates in good yields.

  DOI：

  10.1021/jo990963k

文献信息

• Onium Transfer Reaction of (β,β-Dialkylvinyl)(phenyl)iodonium Tetrafluoroborates via an Alkylidene Carbene Pathway:  Synthesis of Group 15 Alkenyl(triphenyl)- and Group 16 Alkenyl(diphenyl)onium Salts
  作者：Masahito Ochiai、Takuya Sueda、Rie Noda、Motoo Shiro

  DOI：10.1021/jo990963k

  日期：1999.11.1

  Group 15 1-alkenyl(triphenyl)onium (P, As, Sb) tetrafluoroborates were prepared via an onium transfer reaction of alkenyl(phenyl)iodonium tetrafluoroborates under mild conditions. The reaction involves base-induced reductive alpha-elimination of the iodonium salts, followed by nucleophilic trapping of the resulting free alkylidene carbenes with group 15 element-centered nucleophiles. The onium transfer reaction of the alkenyliodonium salts also produced group 16 1-alkenyl(diphenyl)onium (S, Se, Te) tetrafluoroborates in good yields.