prupersin E

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: prupersin E
• 英文别名: [(2R,3S,4S,5R,6R)-6-[[(2R,3S,4S,5R,6R)-6-[(R)-cyano(phenyl)methoxy]-3,4,5-trihydroxyoxan-2-yl]methoxy]-3,4,5-trihydroxyoxan-2-yl]methyl pyridine-3-carboxylate
• 化学式: C₂₆H₃₀N₂O₁₂
• 分子量: 562.53
• InChiKey: LGPUIKWJKFIAIH-LJKDYDQHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  40
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  221
• 氢给体数：
  6
• 氢受体数：
  14

上下游信息

• 下游产品

  中文名称	英文名称	CAS号	化学式	分子量
  苦杏仁苷	amygdalin	29883-15-6	C20H27NO11	457.434

反应信息

• 作为反应物：
  描述：

  prupersin E 在 sodium hydroxide 作用下， 以 甲醇 、 水 为溶剂， 反应 4.0h， 以1 mg的产率得到苦杏仁苷
  参考文献：
  名称：

  Aromatic Glucosides from the Seeds of Prunus davidiana

  摘要：

  Chemical investigation of the seeds of Prunus davidiana afforded seven new aromatic glucosides, i.e., the prupersins A-E (1-5) and compounds 6 and 7, as well as 11 known compounds. The structures of 1-7 were elucidated by spectroscopic data analysis and chemical evidence, and configurations were determined by hydrolysis experiments (1, 2, and 5) or electronic circular dichroism (6). Compounds 1-6 exhibited antioxidant activity aganist Fe2+-cysteine-induced rat liver microsomal lipid peroxidation, with malondialdehyde inhibitory rates of 50-67% and 53-57% at concentrations of 10(-5) and 10(-6) mol/L, respectively.

  DOI：

  10.1021/np4000922

文献信息

• Aromatic Glucosides from the Seeds of <i>Prunus davidiana</i>
  作者：Xiao-Yan Chen、Hong-Qing Wang、Ting Zhang、Chao Liu、Jie Kang、Ruo-Yun Chen、De-Quan Yu

  DOI：10.1021/np4000922

  日期：2013.9.27

  Chemical investigation of the seeds of Prunus davidiana afforded seven new aromatic glucosides, i.e., the prupersins A-E (1-5) and compounds 6 and 7, as well as 11 known compounds. The structures of 1-7 were elucidated by spectroscopic data analysis and chemical evidence, and configurations were determined by hydrolysis experiments (1, 2, and 5) or electronic circular dichroism (6). Compounds 1-6 exhibited antioxidant activity aganist Fe2+-cysteine-induced rat liver microsomal lipid peroxidation, with malondialdehyde inhibitory rates of 50-67% and 53-57% at concentrations of 10(-5) and 10(-6) mol/L, respectively.