1H-indole-4-sulfonic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1H-indole-4-sulfonic acid
• 化学式: C₈H₇NO₃S
• 分子量: 197.214
• InChiKey: WRBMSRKAUBTBMA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  78.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  吲哚 在 sodium hydrogensulfite 、 pyridinium chlorochromate 作用下， 以 neat (no solvent) 为溶剂， 100.0 ℃ 、200.0 kPa 条件下， 反应 0.03h， 以83%的产率得到1H-indole-4-sulfonic acid
  参考文献：
  名称：

  Cornforth 和 Corey-Suggs 试剂作为在无溶剂和微波条件下使用 NaHSO3 磺化芳族和杂芳族化合物的有效催化剂

  摘要：

  摘要 Cornforth 和 Corey-Suggs 试剂重铬酸吡啶 (PDC) 和氯铬酸吡啶 (PCC) 作为有效催化剂，在室温下在乙腈水溶液中使用 NaHSO3 磺化芳族和杂芳族化合物 1-4 小时，而微波辅助反应需要在无溶剂条件下放置 1-4 分钟。这些观察表明微波辅助反应中的显着速率加速。这被解释为当微波通过反应介质时由原位产生的高温和高压引起的分子的大量活化。图形概要

  DOI：

  10.1080/10426507.2020.1782909

文献信息

• [EN] 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10<br/>[FR] ANTAGONISTES DE 2-SULFONYLAMINO-4-HÉTÉROARYL BUTYRAMIDE DE CCR10
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2009126675A1

  公开（公告）日：2009-10-15

  This invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein R1, R2, R4. Ar and Het are as defined herein. The invention also relates to methods of using the compound of formula (I) to treat a diseases and disorders that are mediated or sustained through the activity of CCR10.

  本发明涉及一种具有式（I）的化合物及其药学上可接受的盐，其中R1、R2、R4、Ar和Het如本文中所定义。该发明还涉及使用式（I）的化合物治疗通过CCR10活性介导或维持的疾病和紊乱的方法。
• Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof
  申请人：——

  公开号：US20040019097A1

  公开（公告）日：2004-01-29

  The present invention provides an industrial method that allows to produce an indole derivative trimer with high purity in mass, as well as novel indole derivative trimers obtainable by the method, having high conductivity, high oxidation—reduction potential, high oxidation—reduction capacity, and the excellent cycle characteristics. The present invention relates to a method of producing an indole derivative trimer comprising the step of oxidizing an indole derivative in a reaction solution containing an organic solvent and to the novel trimers produced by the method.

  本发明提供了一种工业方法，可以在反应溶液中氧化含有有机溶剂的吲哚衍生物，从而制备高纯度的吲哚衍生物三聚体，并获得具有高电导率、高氧化还原电位、高氧化还原容量和优异循环特性的新型吲哚衍生物三聚体。本发明涉及一种制备吲哚衍生物三聚体的方法，包括氧化含有有机溶剂的吲哚衍生物的步骤，以及通过该方法制备的新型三聚体。
• Composition containing carbon nanotubes having coating thereof and process for producing them
  申请人：Saitoh Takashi

  公开号：US20060052509A1

  公开（公告）日：2006-03-09

  The object of the present invention is to provide a carbon nanotube composition that does not impair the characteristics of the carbon nanotubes itself, allows the carbon nanotubes to be dispersed or solubilized in a solvent, does not cause separation or aggregation of the carbon nanotubes even during long-term storage, has superior electrical conductivity, film formability and moldability, can be easily coated or covered onto a base material, and the resulting coated film has superior moisture resistance, weather resistance and hardness; a composite having a coated film composed thereof; and, their production methods. In order to achieve this object, the present invention provides a carbon nanotube composition that contains a conducting polymer (a) or heterocyclic compound trimer (i), a solvent (b) and carbon nanotubes (c), and may additionally contain a high molecular weight compound (d), a basic compound (e), a surfactant (f), a silane coupling agent (g) and colloidal silica (h) as necessary; a composite having a coated film composed of the composition; and, their production methods.

  本发明的目的是提供一种碳纳米管组合物，不会影响碳纳米管本身的特性，使碳纳米管可以分散或溶解在溶剂中，在长期储存期间不会导致碳纳米管分离或聚集，具有优异的电导性、成膜性和成型性，可以轻松地涂覆或覆盖在基材上，所得到的涂层膜具有优异的防潮性、耐候性和硬度；一种由涂层膜组成的复合材料；以及它们的生产方法。为了实现这一目的，本发明提供了一种碳纳米管组合物，其中包含导电聚合物(a)或杂环化合物三聚体(i)、溶剂(b)和碳纳米管(c)，并可根据需要另外包含高分子量化合物(d)、碱性化合物(e)、表面活性剂(f)、硅烷偶联剂(g)和胶体二氧化硅(h)；一种由该组合物组成的涂层膜复合材料；以及它们的生产方法。
• Carbon Nanotube Composition, Composite Having a Coated Film Composed of the Same, and Their Production Methods
  申请人：SAITOH Takashi

  公开号：US20090321688A1

  公开（公告）日：2009-12-31

  The object of the present invention is to provide a carbon nanotube composition that does not impair the characteristics of the carbon nanotubes itself, allows the carbon nanotubes to be dispersed or solubilized in a solvent, does not cause separation or aggregation of the carbon nanotubes even during long-term storage, has superior electrical conductivity, film formability and moldability, can be easily coated or covered onto a base material, and the resulting coated film has superior moisture resistance, weather resistance and hardness; a composite having a coated film composed thereof; and, their production methods. In order to achieve this object, the present invention provides a carbon nanotube composition that contains a conducting polymer (a) or heterocyclic compound trimer (i), a solvent (b) and carbon nanotubes (c), and may additionally contain a high molecular weight compound (d), a basic compound (e), a surfactant (f), a silane coupling agent (g) and colloidal silica (h) as necessary; a composite having a coated film composed of the composition; and, their production methods.

  本发明的目的是提供一种碳纳米管组合物，不会损害碳纳米管本身的特性，可以使碳纳米管分散或溶解于溶剂中，在长期存储期间不会导致碳纳米管分离或聚集，具有优异的电导率、膜成形性和成型性，可以轻松涂覆或覆盖在基材料上，并且所得到的涂层膜具有优异的防潮性、耐候性和硬度；一种由该组合物组成的涂层膜复合材料；以及它们的生产方法。为了实现这一目的，本发明提供了一种碳纳米管组合物，它包含导电聚合物(a)或杂环化合物三聚体(i)、溶剂(b)和碳纳米管(c)，并可以根据需要另外包含高分子化合物(d)、碱性化合物(e)、表面活性剂(f)、硅烷偶联剂(g)和胶体二氧化硅(h)；一种由该组合物组成的涂层膜复合材料；以及它们的生产方法。
• METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF
  申请人：Mitsubishi Rayon Co., Ltd.

  公开号：EP1327632A1

  公开（公告）日：2003-07-16

  The present invention provides an industrial method that allows to produce an indole derivative trimer with high purity in mass, as well as novel indole derivative trimers obtainable by the method, having high conductivity, high oxidation - reduction potential, high oxidation - reduction capacity, and the excellent cycle characteristics. The present invention relates to a method of producing an indole derivative trimer comprising the step of oxidizing an indole derivative in a reaction solution containing an organic solvent and to the novel trimers produced by the method.

  本发明提供了一种工业方法，该方法可生产出高纯度的吲哚衍生物三聚体，以及可通过该方法获得的新型吲哚衍生物三聚体，该三聚体具有高导电性、高氧化-还原电位、高氧化-还原能力和优异的循环特性。本发明涉及一种生产吲哚衍生物三聚体的方法，该方法包括在含有有机溶剂的反应溶液中氧化吲哚衍生物的步骤，还涉及用该方法生产的新型三聚体。