3,3',4',5,5',7-hexahydroxy-α-hydroxychalcone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 3,3',4',5,5',7-hexahydroxy-α-hydroxychalcone
• 英文别名: 2-hydroxy-1-(2,4,6-trihydroxyphenyl)-3-(3,4,5-trihydroxyphenyl)prop-2-en-1-one
• 化学式: C₁₅H₁₂O₈
• 分子量: 320.255
• InChiKey: HRUDMFBGGVILSJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  23.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  158.68
• 氢给体数：
  7.0
• 氢受体数：
  8.0

反应信息

• 作为产物：
  描述：

  杨梅素 在 ammonium hydroxide 作用下， 以 乙醇 为溶剂， 反应 1.5h， 以86%的产率得到3,3',4',5,5',7-hexahydroxy-α-hydroxychalcone
  参考文献：
  名称：

  Chemical modification of the natural flavonoid myricetin

  摘要：

  A review is presented of our own results on the synthesis of nitro-, amino-, azo-, and bromo- derivatives of myricetin, as a result which 19 new derivatives have been obtained The compounds synthesized are of interest as substances with potential antitumoral, antimicrobial, antifungal, antioxidant, and antitubercular activities.

  DOI：

  10.1007/bf02238204

文献信息

• Chemical modification of the natural flavonoid myricetin
  作者：V. V. Polyakov

  DOI：10.1007/bf02238204

  日期：1999.1

  A review is presented of our own results on the synthesis of nitro-, amino-, azo-, and bromo- derivatives of myricetin, as a result which 19 new derivatives have been obtained The compounds synthesized are of interest as substances with potential antitumoral, antimicrobial, antifungal, antioxidant, and antitubercular activities.