2,3,5-trimethyl-6-phenethyl-1,4-benzoquinone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3,5-trimethyl-6-phenethyl-1,4-benzoquinone
• 英文别名: 2,3,5-Trimethyl-6-(2-phenylethyl)cyclohexa-2,5-diene-1,4-dione
• 化学式: C₁₇H₁₈O₂
• 分子量: 254.329
• InChiKey: YNGUUTNZAXWYQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  杜醌 、 benzyl p-methylphenyl telluride 以 苯 为溶剂， 反应 12.0h， 以38%的产率得到5,6-dibenzyl-2,3,5,6-tetramethyl-cyclohex-2-ene-1,4-dione
  参考文献：
  名称：

  自由基介导的有机碲化合物与醌的偶联合成取代醌的新途径

  摘要：

  由相应的有机碲化合物产生的以碳为中心的自由基在光热条件下与各种醌反应，以中等至极好的收率得到单加成产物。该反应可用于合成聚异戊二烯基醌类天然产物和C-糖苷。

  DOI：

  10.1016/s0040-4020(02)00784-6

文献信息

• DERMATOLOGICAL COMPOSITIONS WITH ANTI-AGING AND SKIN EVEN-TONING PROPERTIES
  申请人：Hinman Andrew W.

  公开号：US20100010100A1

  公开（公告）日：2010-01-14

  The present invention relates to methods and compositions comprising benzoquinones such as Duroquinone, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.
• [EN] DERMATOLOGICAL COMPOSITIONS WITH ANTI-AGING AND SKIN EVEN-TONING PROPERTIES<br/>[FR] COMPOSITIONS DERMATOLOGIQUES AVEC DES PROPRIÉTÉS D'ANTIVIEILLISSEMENT ET D'HOMOGÉNÉISATION DE LA COULEUR DE LA PEAU
  申请人：EDISON PHARMACEUTICALS INC

  公开号：WO2010005989A1

  公开（公告）日：2010-01-14

  The present invention relates to methods and compositions comprising benzoquinones such as Duroquinone, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.
• A new synthetic route to substituted quinones by radical-mediated coupling of organotellurium compounds with quinones
  作者：Shigeru Yamago、Masahiro Hashidume、Jun-ichi Yoshida

  DOI：10.1016/s0040-4020(02)00784-6

  日期：2002.8

  Carbon-centered radicals generated from the corresponding organotellurium compounds react with a variety of quinones under photo-thermal conditions to give the monoaddition product in moderate to excellent yield. The reaction can be used for the synthesis of polyprenyl quinoid natural products and C-glycosides.

  由相应的有机碲化合物产生的以碳为中心的自由基在光热条件下与各种醌反应，以中等至极好的收率得到单加成产物。该反应可用于合成聚异戊二烯基醌类天然产物和C-糖苷。