Allene carboxylates, scarcely used as Michael acceptors, serve as acceptors in the annulation with phthalides in the presence of LDA and provide a one-pot synthesis of naphtho[c]furanones in very good yields. This tandem annulation is proposed to proceed via transposition of the hydroxy group resulting from the initial annulation.
几乎不用作迈克尔受体的
丙二烯羧酸盐在
LDA存在下与
邻苯二甲酸酯成环时用作受体,并以非常高的收率提供一锅法合成
萘并[ c ]
呋喃酮。提出这种串联环化是通过由初始环化产生的羟基的转位进行的。