citric acid-chloride

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: citric acid-chloride
• 英文别名: citric chloride；2-(2-Chloro-2-oxoethyl)-2-hydroxybutanedioic acid
• 化学式: C₆H₇ClO₆
• 分子量: 210.571
• InChiKey: SNDNGIDFIVPCRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  112
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N-氨乙基哌嗪 、 citric acid-chloride 以 四氢呋喃 为溶剂， 反应 3.0h， 生成
  参考文献：
  名称：

  一种多响应荧光探针及其制备方法

  摘要：

  本发明公开了一种多响应荧光探针及其制备方法。本发明提供的荧光探针的结构式为：。本发明同时提供了该荧光探针的制备方法，包括如下步骤：(1)惰性气氛下，柠檬酸和氯化亚砜发生酰氯化反应得到柠檬酰氯；(2)惰性气氛下，N‑氨乙基哌嗪和柠檬酰氯发生酰胺化反应即得荧光探针。本发明提供的荧光探针对pH具有良好响应，在PH=10~12范围内探针的荧光强度线性增强，实现对pH值的精准测定；在PH=12时能够定性定量检测汞离子，以及通过巯基汞离子的弱相互作用检测谷胱甘肽。另外，该探针具有制备简便，原料成本低，对pH值、汞离子和谷胱甘肽响应迅速，灵敏，易于推广和应用等优点。

  公开号：

  CN109761933A
• 作为产物：
  描述：

  柠檬酸 在 氯化亚砜 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 生成 citric acid-chloride
  参考文献：
  名称：

  一种多响应荧光探针及其制备方法

  摘要：

  本发明公开了一种多响应荧光探针及其制备方法。本发明提供的荧光探针的结构式为：。本发明同时提供了该荧光探针的制备方法，包括如下步骤：(1)惰性气氛下，柠檬酸和氯化亚砜发生酰氯化反应得到柠檬酰氯；(2)惰性气氛下，N‑氨乙基哌嗪和柠檬酰氯发生酰胺化反应即得荧光探针。本发明提供的荧光探针对pH具有良好响应，在PH=10~12范围内探针的荧光强度线性增强，实现对pH值的精准测定；在PH=12时能够定性定量检测汞离子，以及通过巯基汞离子的弱相互作用检测谷胱甘肽。另外，该探针具有制备简便，原料成本低，对pH值、汞离子和谷胱甘肽响应迅速，灵敏，易于推广和应用等优点。

  公开号：

  CN109761933A

文献信息

• High concentration encapsulation of water soluble-materials
  申请人：Monsanto Company

  公开号：EP0148169A2

  公开（公告）日：1985-07-10

  This invention relates to a process for encapsulation, and particularly to the production of small or minute capsules constituted by a skin or thin wall of polymeric material e.g., polyurea, polyamide, polysulfonamide, polyester, polycarbonate, or polyurethane, which involves first providing an organic liquid (continuous phase liquid) containing an oil soluble alkylated polyvinylpyrrolidone emulsifier A discontinuous (aqueous) phase liquid containing a water-soluble material, which is the material to be encapsulated, plus a first shell wall component; is dispersed in the continuous phase liquid to form a water-in-oil emulsion. The second shell wall component is added to the water-in-oil emulsion whereupon the first shell wall component reacts with the second shell wall component to form a solid polymeric shell wall about the material to be encapsulated. The capsules formed may be directly used as in the form of an organic suspension, i.e., a suspension of microcapsules in the organic liquid.

  本发明涉及一种封装工艺，特别是由聚合材料（如聚脲、聚酰胺、聚磺酰胺、聚酯、聚碳酸酯或聚氨酯）的表皮或薄壁构成的小型或微小胶囊的生产工艺、首先提供一种有机液体（连续相液体），其中含有一种油溶性烷基化聚乙烯吡咯烷酮乳化剂；然后将一种不连续（水性）相液体分散在连续相液体中，形成油包水型乳液。将第二壳壁组分加入油包水型乳液中，此时第一壳壁组分与第二壳壁组分发生反应，形成关于待封装材料的固体聚合物壳壁。形成的胶囊可以以有机悬浮液的形式直接使用，即微胶囊在有机液体中的悬浮液。
• Microencapsulated naturally occuring pyrethrins
  申请人：PENNWALT CORPORATION

  公开号：EP0172934A1

  公开（公告）日：1986-03-05

  A process for microencapsulating naturally-occurring pyrethrins with a polyamide-polyurea shell by interfacial condensation which includes slowly adding an amine reactant to an aqueous emulsion containing the pyrethrin, an isocyanate, and an acyl halide with the requirement that at least one of said isocyanate or said acyl halide is polyfunctional, to provide free flowing capsules having a polyamide-polyurea wall encapsulating the natural pyrethrin.

  一种通过界面缩合将天然除虫菊酯与聚酰胺-聚脲外壳微胶囊化的工艺，包括向含有除虫菊酯、异氰酸酯和酰基卤的水乳液中缓慢加入胺反应物，要求所述异氰酸酯或所述酰基卤中至少有一种是多官能团的，以提供具有封装天然除虫菊酯的聚酰胺-聚脲壁的自由流动胶囊。
• Microencapsulated Pyrethroids
  申请人：ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.)

  公开号：EP0183999A1

  公开（公告）日：1986-06-11

  A sprayable insecticidal composition of low fish toxicity of a mixture in water of microcapsules comprised of a pyrethroid (synthetic pyrethrin) contained within an encapsulating wall of a cross-linked polymeric material, and methods of preparation and method of use of the composition on a wide variety of crops and aquatic sites infested with a broad spectrum of undesirable insects.

  一种低鱼类毒性的可喷洒杀虫组合物，由包含在交联聚合物材料封装壁中的拟除虫菊酯（合成拟除虫菊酯）微胶囊水混合物组成，以及该组合物的制备方法和使用方法，可用于多种作物和遭受广谱不良昆虫侵扰的水域。
• Water-dispersible granules and process for the preparation thereof
  申请人：Monsanto Company

  公开号：EP0252896A2

  公开（公告）日：1988-01-13

  The invention is directed to a pesticide composition comprising free flowing, essentially spherical, water-dispersible granules wherein said water-dispersible granules are from about 150 to about 850 microns in diameter; wherein said granules contain up to about 8.0% by weight moisture; wherein each individual water-dispersible granule is an aggregation of individual spherical microcapsules which contain at least one water-insoluble pesticide within a polymeric shell wall; and wherein said water-dispersible granule disintegrates upon contact with water to release said individual microcapsules. The invention also relates to dry flowable pesticidal formulations of the above water-dispersible granules, together with formulation adjuvants. The invention is further directed to a process for preparing a water-dispersible granule comprising: (a) forming an aqueous suspension compris­ing discrete microcapsules containing at least one water-insoluble pesticide within a polymeric shell wall suspended in an aqueous liquid; and (b) forming droplets of said aqueous suspension and spray drying said droplets to form essentially spherical water-dispersible granules which are from about 150 to about 850 microns in diameter and which contain up to about 8.0% moisture, wherein each water-dispersible granule is an aggregation of said microcapsules.

  本发明涉及一种农药组合物，该组合物包含自由流动的、基本为球形的水分散粒剂，其中所述水分散粒剂的直径约为 150 至约 850 微米；所述粒剂含有高达约 8.0%(重量)的水分；其中每个水分散粒剂是单个球形微胶囊的聚集体，在聚合物壳壁内含有至少一种水不溶性农药；以及其中所述水分散粒剂在与水接触时崩解，释放出所述单个微胶囊。 本发明还涉及上述水分散粒剂的干燥可流动农药制剂，以及制剂佐剂。 本发明还涉及一种制备水分散粒剂的工艺，包括 (a) 形成水性悬浮液，该悬浮液由离散的微胶囊组成，微胶囊的聚合物壳壁中至少含有一种水不溶性农药，悬浮在水性液体中；以及 (b) 形成所述水性悬浮液的液滴，并喷雾干燥所述液滴，以形成直径约 150 至约 850 微米且含水量高达约 8.0%的基本球形水分散粒剂，其中每个水分散粒剂都是所述微胶囊的聚集体。
• Formulations of water-dispersible granules and process for preparation thereof
  申请人：Monsanto Company

  公开号：EP0252897A2

  公开（公告）日：1988-01-13

  The invention herein relates to dry flowable water-dispersible granular formulations and to a process for the preparation thereof. In particular, the water-dispersible granular formulations of this invention comprise a mixture of aggregates of microcapsules of water-insoluble pesticide, e.g., alachlor, or a plant growth regulant encapsulated within a polymeric shell wall and at least one other pesticide, e.g., atrazine or a salt of glyphosate, which is non-encapsulated. The water-dispersible granular formulations of the invention are prepared by mixing appropriate quantities of an aqueous dispersion of the encapsulated component, the non-encapsulated component and formulation adjuvants to form a slurry of the desired viscosity which can be directly extruded then dried or the slurry in more dilute, less viscous form may be spray dried, or agglomerated in fluid beds or rotating disc agglomerators.

  本发明涉及可流动的干性水分散粒剂及其制备工艺。 特别是，本发明的水分散粒状制剂由包封在聚合物壳壁内的水不溶性农药（如甲草胺或植物生长调节剂）的微胶囊聚集体和至少一种其他农药（如阿特拉津或草甘膦盐）的混合物组成。 本发明的水分散粒状制剂的制备方法是：将适量的包封成分、非包封成分和制剂佐剂的水分散液混合，形成所需粘度的浆液，可直接挤出然后干燥，或将稀释度较高、粘度较低的浆液喷雾干燥，或在流化床或旋转圆盘造粒机中造粒。