4-hydroxybutyl-bicyclo[2.2.1]hept-5-ene-2-carboxylate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-hydroxybutyl-bicyclo[2.2.1]hept-5-ene-2-carboxylate
• 英文别名: 4-Hydroxybutyl bicyclo[2.2.1]hept-5-ene-2-carboxylate
• 化学式: C₁₂H₁₈O₃
• 分子量: 210.273
• InChiKey: OZCOWTCSHRARFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3,4,6-三邻苄基半乳醛 、 4-hydroxybutyl-bicyclo[2.2.1]hept-5-ene-2-carboxylate 在 2,4,6-tri-tertiary-butylpyridinium hydrochloride salt 作用下， 以 二氯甲烷 为溶剂， 反应 9.0h， 以85%的产率得到4-hydroxybutyl-bicyclo[2.2.1]hept-5-ene-2-carboxylate-2-deoxy-3,4,6-tri-O-benzyl-α-D-galactopyranoside
  参考文献：
  名称：

  立体受阻的2,4,6-三叔丁基吡啶鎓盐作为单氢键供体用于糖类的高度立体选择性糖基化反应

  摘要：

  我们在这里证明，应变和庞大的质子化的2,4,6-三叔丁基吡啶盐可作为各种糖类的高度立体选择性糖基化的有效催化剂。此外，作用机理涉及有趣的单个氢键介导的糖基质子化，而不是通过通常构想的布朗斯台德酸途径。抗衡阴离子在反应结果中也起作用。

  DOI：

  10.1021/acs.orglett.9b00626
• 作为产物：
  描述：

  1,4-丁二醇 、 5-降冰片烯-2-羧酸 在 4-二甲氨基吡啶 、 N,N'-二环己基碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 以76%的产率得到4-hydroxybutyl-bicyclo[2.2.1]hept-5-ene-2-carboxylate
  参考文献：
  名称：

  立体受阻的2,4,6-三叔丁基吡啶鎓盐作为单氢键供体用于糖类的高度立体选择性糖基化反应

  摘要：

  我们在这里证明，应变和庞大的质子化的2,4,6-三叔丁基吡啶盐可作为各种糖类的高度立体选择性糖基化的有效催化剂。此外，作用机理涉及有趣的单个氢键介导的糖基质子化，而不是通过通常构想的布朗斯台德酸途径。抗衡阴离子在反应结果中也起作用。

  DOI：

  10.1021/acs.orglett.9b00626

文献信息

• Semiconductor device using polymer-containing photoresist, and process for manufacturing the same
  申请人：——

  公开号：US20010053834A1

  公开（公告）日：2001-12-20

  The present invention relates to a semiconductor device using a copolymer-containing photoresist, and a process for manufacturing the same. As a norbornene derivative (monomer) having a hydrophilic group is synthesized and introduced to the backbone chain of a polymer, the polymer according to the present invention has excellent etching resistance and heat resistance, which are the characteristic points of alicyclic olefin structure, and provide excellent resolution due to prominent enhancement of adhesiveness resulted from introducing a hydrophilic group (—OH).

  本发明涉及一种使用共聚物含有的光阻的半导体器件及其制造方法。通过合成具有亲水基的萘并衍生物（单体）并将其引入聚合物的骨架链中，本发明的聚合物具有杂环烯烃结构的特点，具有优异的蚀刻抗性和耐热性，并由于引入亲水基（—OH）而显着提高了粘附性，从而提供了优异的分辨率。
• OPEN-RING COPOLYMER, HYDROGENATED OPEN-RING COPOLYMER, PROCESSES FOR PRODUCTION OF BOTH, AND COMPOSITIONS
  申请人：Zeon Corporation

  公开号：EP1408064A1

  公开（公告）日：2004-04-14

  A ring-opened metathesis copolymer and its hydrogenated product having a desired monomer unit ratio and a high molecular weight and having hydroxyl groups or hydroxycarbonyl groups can be obtained by conducting a ring-opening metathesis copolymerization of a norbornene-type monomer having hydroxyl groups or hydroxycarbonyl groups with an unsubstituted norbornene-type monomer having at least three rings in the presence of a catalyst predominantly comprised of an organic ruthenium compound having coordinated therewith a neutral electron-donating ligand, and, if desired, hydrogenating the resulting copolymer. The thus-obtained ring-opened metathesis copolymer and its hydrogenation product are characterized by having a low water absorption, good adhesion to metal and other materials, good compatibility with a curing agent and other compounds, and high heat resistance, and exhibiting reduced signal retardation and signal noise.

  在主要由有机钌化合物组成的催化剂存在下，将具有羟基或羟羰基的降冰片烯类单体与具有至少三个环的未取代降冰片烯类单体进行开环偏析共聚，可获得具有所需单体单元比和高分子量且具有羟基或羟羰基的开环偏析共聚物及其氢化产物、如果需要，对得到的共聚物进行氢化。这样得到的开环偏聚共聚物及其氢化产物的特点是吸水性低，与金属和其他材料的粘附性好，与固化剂和其他化合物的相容性好，耐热性高，并能减少信号延迟和信号噪声。
• Ring-opened copolymer, hydrogenated ring-opened copolymer, process for producing thereof, and compositions
  申请人：ZEON CORPORATION

  公开号：EP1803761A1

  公开（公告）日：2007-07-04

  A ring-opened metathesis copolymer and its hydrogenated product having a desired monomer unit ratio and a high molecular weight and having hydroxyl groups can be obtained by conducting a ring-opening metathesis copolymerization of a norbornene-type monomer having hydroxyl groups with an unsubstituted norbornene-type monomer having at least three rings in the presence of a catalyst predominantly comprised of an organic ruthenium compound having coordinated therewith a neutral electron-donating ligand, and, if desired, hydrogenating the resulting copolymer. The thus-obtained ring-opened metathesis copolymer and its hydrogenation product are characterized by having a low water absorption, good adhesion to metal and other materials, good compatibility with a curing agent and other compounds, and high heat resistance, and exhibiting reduced signal retardation and signal noise.

  在主要由有机钌化合物组成的催化剂存在下，将具有羟基的降冰片烯类单体与具有至少三个环的未取代降冰片烯类单体进行开环偏析共聚，并在需要时对所得共聚物进行氢化，可获得具有所需单体单元比和高分子量且具有羟基的开环偏析共聚物及其氢化产物。这样得到的开环偏聚共聚物及其氢化产物的特点是吸水性低，与金属和其他材料的粘附性好，与固化剂和其他化合物的相容性好，耐热性高，并能减少信号延迟和信号噪声。
• Process for producing circuit substrates
  申请人：——

  公开号：US20040029043A1

  公开（公告）日：2004-02-12

  A curable composition contains an insulating resin such as an alicyclic olefin polymer or an aromatic polyether polymer, a nitrogen-type curing agent such as a 1,3-diallyl-5-glycidylisocyanurate, and an ultraviolet-ray absorbing agent such as a 2-[2-hydroxy-3,5-bis(&agr;,&agr;-dimethylbenzyl)phenyl]benzotriazole. A film is obtained from the curable composition by a solution casting method, is laminated on an inner-layer board and is cured to obtain a multi-layer circuit board.

  一种可固化组合物含有绝缘树脂（如脂环烯烃聚合物或芳香族聚醚聚合物）、氮型固化剂（如 1,3-二烯丙基-5-缩水甘油基异氰尿酸酯）和紫外线吸收剂（如 2-[2-羟基-3,5-双(&agr;,&agr;-二甲基苄基)苯基]苯并三唑）。用溶液浇注法从可固化组合物中获得薄膜，将薄膜层压在内层电路板上，然后固化以获得多层电路板。
• Open-ring copolymer, hydrogenated open-ring copolymer, process for production of both, and compositions
  申请人：——

  公开号：US20040152843A1

  公开（公告）日：2004-08-05

  A ring-opened metathesis copolymer and its hydrogenated product having a desired monomer unit ratio and a high molecular weight and having hydroxyl groups or hydroxycarbonyl groups can be obtained by conducting a ring-opening metathesis copolymerization of a norbornene-type monomer having hydroxyl groups or hydroxycarbonyl groups with an unsubstituted norbornene-type monomer having at least three rings in the presence of a catalyst predominantly comprised of an organic ruthenium compound having coordinated therewith a neutral electron-donating ligand, and, if desired, hydrogenating the resulting copolymer. The thus-obtained ring-opened metathesis copolymer and its hydrogenation product are characterized by having a low water absorption, good adhesion to metal and other materials, good compatibility with a curing agent and other compounds, and high heat resistance, and exhibiting reduced signal retardation and signal noise.

  在主要由有机钌化合物组成的催化剂存在下，将具有羟基或羟羰基的降冰片烯类单体与具有至少三个环的未取代降冰片烯类单体进行开环偏析共聚，可获得具有所需单体单元比和高分子量且具有羟基或羟羰基的开环偏析共聚物及其氢化产物、如果需要，对得到的共聚物进行氢化。这样得到的开环偏聚共聚物及其氢化产物的特点是吸水性低，与金属和其他材料的粘附性好，与固化剂和其他化合物的相容性好，耐热性高，并能减少信号延迟和信号噪声。