Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
申请人:Merck Sharp & Dohme Corp.
公开号:US09364482B2
公开(公告)日:2016-06-14
The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system. (I)
本发明涉及公式I的化合物,该化合物可用作丙型肝炎病毒(HCV)NS5B聚合酶抑制剂,以及合成该化合物和使用该化合物抑制HCV NS5B聚合酶活性、治疗或预防HCV感染以及在基于细胞的系统中抑制HCV病毒复制和/或病毒产生的用途。(I)