N,N,N',N'-tetramethyl-O-methylisouronium trifluoromethanesulfonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N,N,N',N'-tetramethyl-O-methylisouronium trifluoromethanesulfonate
• 英文别名: N,N,N',N'-tetramethyl-O-methylisouronium triflate；[Dimethylamino(methoxy)methylidene]-dimethylazanium;trifluoromethanesulfonate；[dimethylamino(methoxy)methylidene]-dimethylazanium;trifluoromethanesulfonate
• 化学式: CF₃O₃S*C₆H₁₅N₂O
• 分子量: 280.268
• InChiKey: JRHWBVAAQXWPLU-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.13
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  81.1
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  tris(pentafluoroethyl)trifluorophosphoric acid 、 N,N,N',N'-tetramethyl-O-methylisouronium trifluoromethanesulfonate 以 水 为溶剂， 以96.8%的产率得到N,N,N',N'-tetramethyl-O-methylisouronium tris(pentafluoroethyl)trifluorphosphate
  参考文献：
  名称：

  [DE] IONISCHE FLÜSSIGKEITEN MIT URONIUM- ODER THIOURONIUM-KATIONEN
  [EN] IONIC LIQUID COMPRISING URONIUM CATIONS OR THIOURONIUM CATIONS
  [FR] LIQUIDES IONIQUES CONTENANT DES CATIONS D'URONIUM OU DE THIOURONIUM

  摘要：

  这项发明涉及具有硫脲或尿素阳离子的盐，它们的制备方法以及它们作为离子液体的用途。

  公开号：

  WO2004106287A1
• 作为产物：
  描述：

  1,1,3,3-四甲基脲 、 三氟甲烷磺酸甲酯 反应 21.0h， 以100%的产率得到N,N,N',N'-tetramethyl-O-methylisouronium trifluoromethanesulfonate
  参考文献：
  名称：

  三氟甲磺酸盐阴离子液体的简便合成及其性质

  摘要：

  通过有机碱（胺、膦或杂环化合物）与三氟甲磺酸甲酯和乙酯（三氟甲磺酸甲酯和乙酯）的直接烷基化，开发了一种无溶剂和无卤素的高纯度三氟甲磺酸盐离子液体合成方法。在通过本发明的方法制备三氟甲磺酸甲酯和乙酯中，廉价且无毒的碳酸二甲酯和碳酸二乙酯用作甲基和乙基的来源。确定并讨论了含有三氟甲磺酸根阴离子的离子液体的性质。

  DOI：

  10.3390/molecules17055319

文献信息

• Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array
  申请人：CustomArray, Inc.

  公开号：US10006131B1

  公开（公告）日：2018-06-26

  There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.

  本发明公开了一种用于电极微阵列的电化学解锁溶液。还进一步公开了一种使用该电化学解锁溶液在电极阵列上进行电化学合成的方法。该溶液和方法用于去除酸性保护基团，以便在电极微阵列上合成寡核苷酸、肽、小分子或聚合物，同时大幅提高与活性电极的解锁隔离度。该方法包括向电极阵列中的至少一个电极施加电压或电流。电极阵列被电化学解锁溶液覆盖。
• ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE
  申请人：Combimatrix Corporation

  公开号：EP1805206A2

  公开（公告）日：2007-07-11
• ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY
  申请人：Combimatrix Corporation

  公开号：EP1869061A2

  公开（公告）日：2007-12-26
• Ionic Liquids Having Uronium Or Thiouronium Cations
  申请人：Ignatyev Nikolai (Myloka)

  公开号：US20070287869A1

  公开（公告）日：2007-12-13

  The present invention relates to salts having thiouronium or uronium cations, to processes for the preparation thereof, and to the use thereof as ionic liquids.
• IONIC LIQUID MEDIUMS FOR HOLDING SOLID PHASE PROCESS GAS PRECURSORS
  申请人：Torres, JR. Robert

  公开号：US20090320771A1

  公开（公告）日：2009-12-31

  Ionic fluid mixtures are described that include an ionic liquid and a solid-phase material. The ionic liquid and the solid-phase material are selected to convert the solid-phase material into a gas phase material at a temperature that is lower than a conversion of the ionic liquid into a gas phase ionic material. In addition, methods of supplying a gaseous precursor to an application are described. These methods include providing a mixture of an ionic liquid and a solid-phase starting material, heating the mixture to a temperature that vaporizes at least a portion of the solid-phase starting material into the gaseous precursor, and transporting the gaseous precursor from the mixture to the application that utilizes the gaseous precursor.