dimethyl allylphenylmalonate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: dimethyl allylphenylmalonate
• 英文别名: Dimethyl 2-phenyl-2-prop-2-enylpropanedioate
• 化学式: C₁₄H₁₆O₄
• 分子量: 248.279
• InChiKey: OIPLJWIJSVZGCW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  乙酸烯丙酯 、 dimethyl 2-phenylmalonate 在 microencapsulated Pd(PPh₃) N,O-双三甲硅基乙酰胺 、 potassium acetate 、 三苯基膦 作用下， 以 乙腈 为溶剂， 反应 12.0h， 以90%的产率得到dimethyl allylphenylmalonate
  参考文献：
  名称：

  Microencapsulated Palladium Catalysts: Allylic Substitution and Suzuki Coupling Using a Recoverable and Reusable Polymer-Supported Palladium Catalyst

  摘要：

  DOI：

  10.1002/1521-3773(20010917)40:18<3469::aid-anie3469>3.0.co;2-t

文献信息

• The Polymer Incarcerated Method for the Preparation of Highly Active Heterogeneous Palladium Catalysts
  作者：Ryo Akiyama、Shū Kobayashi

  DOI：10.1021/ja029146j

  日期：2003.3.1

  incarcerated (PI) method" for preparing a heterogeneous palladium catalyst has been developed. The method is operationally simple, and the Pd catalyst prepared (PI Pd) is highly active for hydrogenation, carbon-carbon, and carbon-oxygen bond-forming reactions. Remarkable points are that the activity of PI Pd is higher than that of homogeneous Pd catalysts and that PI Pd is recovered by simple filtration

  开发了一种名为“聚合物包埋（PI）法”的制备多相钯催化剂的新方法。该方法操作简单，制备的Pd催化剂(PI Pd)对加氢、碳-碳和碳-氧键形成反应具有高活性。值得注意的是，PI Pd的活性高于均相Pd催化剂，PI Pd通过简单过滤回收并重复使用多次而不会损失活性。该催化剂有望替代许多多相钯催化剂，尤其是Pd/C，常用于学术界和工业界，但回收困难。
• Palladium catalyst composition
  申请人：Kobayashi Shu

  公开号：US20060019822A1

  公开（公告）日：2006-01-26

  The present invention discloses 1) a catalyst composition consisting of a crosslinked organic polymer compound and a palladium catalyst, wherein said catalyst is physically carried on said crosslinked organic polymer compound, 2) a manufacturing method of the above catalyst composition 1), characterized by homogenizing a straight chain organic polymer compound, having a crosslinkable functional group, and a palladium catalyst in a solvent dissolving said straight chain organic polymer compound, then depositing a composition thus formed and subjecting the crosslinkable functional group in said deposit to a crosslinking reaction, 3) a method for substitution reaction at an allyl position, characterized by reacting an allyl carbonate and a neucleophilic agent in the presence of the above catalyst composition 1), and 4) a method for oxidizing an alcohol, characterized by subjecting the above catalyst composition 1) to reaction with an alcohol. The catalyst composition of the present invention can be safely and easily handled without danger of spontaneous ignition, and the like, and is extremely useful as a catalyst for various chemical reactions, and further activity thereof is not decreased by repeated use thereof and a metal catalyst does not leak from a polymer compound which is a carrier thereof.

  本发明揭示了以下内容：1）由交联有机聚合物化合物和钯催化剂组成的催化剂组合物，其中所述催化剂物理上载在所述交联有机聚合物化合物上，2）上述催化剂组合物1）的制造方法，其特征在于在溶解所述直链有机聚合物化合物的溶剂中均质化具有可交联功能基团的直链有机聚合物化合物和钯催化剂，然后沉积形成的组合物并使所述沉积物中的可交联功能基团发生交联反应，3）一种在烯丙基位置进行取代反应的方法，其特征在于在上述催化剂组合物1）的存在下，将烯丙基碳酸酯和亲核试剂反应，4）一种氧化醇的方法，其特征在于将上述催化剂组合物1）与醇反应。本发明的催化剂组合物可以安全、容易地处理，没有自发着火等危险，并且极其有用作为各种化学反应的催化剂，其活性不会因重复使用而降低，并且金属催化剂不会从作为载体的聚合物化合物中泄漏。
• PALLADIUM CATALYST COMPOSITION
  申请人：Wako Pure Chemical Industies, Ltd.

  公开号：EP1537913B1

  公开（公告）日：2009-07-01
• MICROENCAPSULATED METAL CATALYST
  申请人：Japan Science and Technology Agency

  公开号：EP1386663B1

  公开（公告）日：2009-04-15
• Microencapsulated metal catalyst
  申请人：Kobayashi Shu

  公开号：US20080076662A1

  公开（公告）日：2008-03-27

  A microencapsulated Group VIII metal catalyst which is stable even in air, easy to recover, and reusable is disclosed. It comprises a polymer with side chains containing an aromatic substituent, and a metal catalyst comprising a Group VIII metal encapsulated in to this polymer.