F-4-Protoadamantanone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: F-4-Protoadamantanone
• 英文别名: 1,2,2,3,5,5,6,7,7,8,9,9,10,10-tetradecafluorotricyclo[4.3.1.03,8]decan-4-one
• 化学式: C₁₀F₁₄O
• 分子量: 402.087
• InChiKey: IAKZAZQBCQRGFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.61
• 重原子数：
  25.0
• 可旋转键数：
  0.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  F-4-Protoadamantanone 以 一氟三氯甲烷 为溶剂， 反应 528.0h， 生成 F-Noradamantanone
  参考文献：
  名称：

  Syntheses and Photochemical Reactions of Perfluorinated Carbonyl-Containing Adamantane Derivatives

  摘要：

  F-4-Oxahomoadamantan-5-one, F-4-protoadamantanone, and F-adamantane-2,4-dione have been synthesized for the first time by aerosol direct fluorination of their corresponding hydrocarbons. UV irradiation of F-4-oxahomoadamantan-5-one produces F-oxaadamantane, the corresponding decarbonylation product: its first reported synthesis. UV irradiation of F-4-protoadamantanone gave F-noradamantane, the same product as from UV irradiation of F-adamantanone. All new products were characterized by mass spectrometry, F-19 NMR, FT-IR spectroscopy, and elemental analysis.

  DOI：

  10.1021/jo00099a013
• 作为产物：
  描述：

  4-protoadamantanone 在 fluorine 作用下， 以 various solvent(s) 为溶剂， 反应 4.5h， 以23.5%的产率得到F-4-Protoadamantanone
  参考文献：
  名称：

  Syntheses and Photochemical Reactions of Perfluorinated Carbonyl-Containing Adamantane Derivatives

  摘要：

  F-4-Oxahomoadamantan-5-one, F-4-protoadamantanone, and F-adamantane-2,4-dione have been synthesized for the first time by aerosol direct fluorination of their corresponding hydrocarbons. UV irradiation of F-4-oxahomoadamantan-5-one produces F-oxaadamantane, the corresponding decarbonylation product: its first reported synthesis. UV irradiation of F-4-protoadamantanone gave F-noradamantane, the same product as from UV irradiation of F-adamantanone. All new products were characterized by mass spectrometry, F-19 NMR, FT-IR spectroscopy, and elemental analysis.

  DOI：

  10.1021/jo00099a013

文献信息

• Adcock James L., Luo Huimin, J. Org. Chem., 59 (1994) N 20, S 5883-5885
  作者：Adcock James L., Luo Huimin

  DOI：——

  日期：——