2-(2-Cyclohexylethoxy)ethanamine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(2-Cyclohexylethoxy)ethanamine
• 英文别名: 2-(2-cyclohexylethoxy)ethanamine
• 化学式: C₁₀H₂₁NO
• 分子量: 171.28
• InChiKey: NJWYQGPUFWRLJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] 6-(5-MEMBERED HETEROARYL)ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF<br/>[FR] 6-(HÉTÉROARYLE À 5 CHAÎNONS)ISOQUINOLIN-3-YL CARBOXAMIDES, LEUR PRÉPARATION ET LEUR UTILISATION
  申请人：SAMUMED LLC

  公开号：WO2019079626A1

  公开（公告）日：2019-04-25

  Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, inflammation, auto-immune diseases and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as neurological conditions/disorders/diseases linked to overexpression of DYRK1A.