4-(1-aminomethyl-1,2-dimethylallyl)benzonitrile

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(1-aminomethyl-1,2-dimethylallyl)benzonitrile
• 英文别名: 4-(1-Amino-2,3-dimethylbut-3-en-2-yl)benzonitrile；4-(1-amino-2,3-dimethylbut-3-en-2-yl)benzonitrile
• 化学式: C₁₃H₁₆N₂
• 分子量: 200.283
• InChiKey: GLZGDJVZHRYOBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  对苯二腈 、 2,3-二甲基-1,3-丁二烯 在 1,2,4-三苯基苯 、 氨 、 N,N,N,N-tetraethylammonium tetrafluoroborate 作用下， 以 水 、 乙腈 为溶剂， 反应 8.0h， 以10%的产率得到4-(1-aminomethyl-1,2-dimethylallyl)benzonitrile
  参考文献：
  名称：

  Redox-photosensitized amination of alkenes and alkadienes with ammonia and alkylamines

  摘要：

  Using 1,2,4-triphenylbenzene as a photosensitizer, the photoamination of alkenes and alkadienes (1), which had no absorption at > 300 nm proceeded efficiently in the presence of p-dicyanobenzene to give addition products by incorporating both amino andp-cyanophenyl groups. The reaction efficiency was discussed in terms of the relationships between 1 and the photosensitizer in their oxidation potentials and the distribution of positive charge on the reaction site of the cation radical of 1 (1(+.)). (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2006.10.064

文献信息

• Redox-photosensitized amination of alkenes and alkadienes with ammonia and alkylamines
  作者：Toshiaki Yamashita、Junichi Itagawa、Daichi Sakamoto、Yuji Nakagawa、Jin Matsumoto、Tsutomu Shiragami、Masahide Yasuda

  DOI：10.1016/j.tet.2006.10.064

  日期：2007.1

  Using 1,2,4-triphenylbenzene as a photosensitizer, the photoamination of alkenes and alkadienes (1), which had no absorption at > 300 nm proceeded efficiently in the presence of p-dicyanobenzene to give addition products by incorporating both amino andp-cyanophenyl groups. The reaction efficiency was discussed in terms of the relationships between 1 and the photosensitizer in their oxidation potentials and the distribution of positive charge on the reaction site of the cation radical of 1 (1(+.)). (c) 2006 Elsevier Ltd. All rights reserved.