十五烷基环氧乙烷 | 22092-38-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 环氧化物
• 中文名称: 十五烷基环氧乙烷
• 中文别名: 1,2-环氧十七烷
• 英文名称: 2-pentadecanyloxirane
• 英文别名: pentadecyl-oxirane；1,2-epoxyheptadecane；Pentadecyloxirane；2-pentadecyloxirane
• CAS: 22092-38-2
• 化学式: C₁₇H₃₄O
• 分子量: 254.456
• InChiKey: XSNXNMMWBCZUSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  18
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2910900090

反应信息

• 作为反应物：
  描述：

  1-硫代甘油 、 十五烷基环氧乙烷 生成 3-(2-hydroxyheptadecylsulfanyl)propane-1,2-diol
  参考文献：
  名称：

  HORODYSKY, A. G.;KAMINSKI, J. M.

  摘要：

  DOI：
• 作为产物：
  描述：

  十七烯 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 生成 十五烷基环氧乙烷
  参考文献：
  名称：

  Ketoalkylphospholipids

  摘要：

  新型酮烷基磷脂类化合物，包括其盐，化学式如下：其中R.sup.1为含有10至20个碳原子的脂肪烃残基，R.sup.2为氢或甲氧基，R.sup.3、R.sup.4和R.sup.5独立地为氢或C.sub.1-5烷基，或##STR2##代表环铵基团，表现出抑制肿瘤细胞增殖和抗真菌活性。

  公开号：

  US04649203A1

文献信息

• Mechanistic Insights from Reaction of α-Oxiranyl-Aldehydes with Cyanobacterial Aldehyde Deformylating Oxygenase
  作者：Debasis Das、Benjamin Ellington、Bishwajit Paul、E. Neil G. Marsh

  DOI：10.1021/cb400772q

  日期：2014.2.21

  corresponding oxiranes. Performing the reaction in D2O allowed the facial selectivity of proton addition to be examined by 1H NMR spectroscopy. The proton is delivered with equal probability to either face of the oxirane ring, indicating the formation of an oxiranyl radical intermediate that is free to rotate during the reaction. Unexpectedly, the enzyme also catalyzes a side reaction in which oxiranyl-aldehydes

  源自脂肪酸的长链脂肪烃的生物合成在自然界中广泛存在。该途径的最后一步涉及将脂肪醛脱羰为相应的烷烃或烯烃。在蓝藻中，这是由醛去甲酰加氧酶催化的。我们已经使用与醛碳相邻的带有环氧乙烷环的底物研究了这种酶的机制。该酶催化这些底物的去甲酰化以产生相应的环氧乙烷。在 D 2 O 中进行反应允许通过1检查质子添加的面部选择性核磁共振谱。质子以相等的概率传递到环氧乙烷环的任一面，表明在反应过程中形成了可自由旋转的环氧乙烷自由基中间体。出乎意料的是，该酶还催化了一个副反应，其中环氧乙烷醛进行串联去甲酰化以提供短两个碳的烷烃。我们提供的证据表明，这涉及在第一步中形成的中间体环氧乙烷基的重排，导致在第二步中进一步去甲酰化的醛。这些观察结果为去甲酰化的自由基机制提供了支持，此外，允许基于环氧乙烷基重排的速率常数的先前测量来估计自由基中间体的寿命。
• Ketoalkylphospholipids
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US04649203A1

  公开（公告）日：1987-03-10

  Novel ketoalkylphospholipids, inclusive of salts thereof, of the formula ##STR1## wherein R.sup.1 is an aliphatic hydrocarbon residue containing 10 to 20 carbon atoms, R.sup.2 is hydrogen or methoxy, and R.sup.3, R.sup.4 and R.sup.5 are independently hydrogen or C.sub.1-5 alkyl, or ##STR2## represents a cyclic ammonio group, exhibit inhibitory activity against multiplication of tumor cells and antifungal activity.

  新型酮烷基磷脂类化合物，包括其盐，化学式如下：其中R.sup.1为含有10至20个碳原子的脂肪烃残基，R.sup.2为氢或甲氧基，R.sup.3、R.sup.4和R.sup.5独立地为氢或C.sub.1-5烷基，或##STR2##代表环铵基团，表现出抑制肿瘤细胞增殖和抗真菌活性。
• Hybrid onium salt
  申请人：Ishihara Masami

  公开号：US20050020710A1

  公开（公告）日：2005-01-27

  The present invention relates to a hybrid type onium salt having an iodonium salt and a sulfonium salt in the molecule, useful, for example, as a cationic type photopolymerization initiator and an acid generator for a chemically amplified resist and provides a hybrid type onium salt shown by the general formula [1]: [wherein R 1 to R 3 are each independently a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group or an amino group which maybe substituted; Q 1 is a direct-linkage, an oxygen atom, a sulfur atom or a lower alkylene chain; T 1 is an alkylene group or an arylene group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted; and R 4 is an alkyl group, an alkenyl group, an aryl group or an aralkyl group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted or a group shown by the general formula [2]: (wherein R 5 to R 7 are each independently a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group or an amino group which maybe substituted; Q 2 is a direct-linkage, an oxygen atom, a sulfur atom or a lower alkylene chain; T 2 an alkylene group or an arylene group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted; A 3 is a counter anion; m is an integer of 0 to 4; and two ns are each independently an integer of 0 to 5); A 1 and A 2 are each independently a counter anion; and m and n are the same as described above], and a polymerization initiator or an acid generator, comprising said onium salt.

  本发明涉及一种杂化型离子盐，其分子中具有碘化离子盐和亚砜盐，例如，作为阳离子型光聚合引发剂和化学放大型抗蚀剂的酸发生剂有用，并提供由通式[1]所示的杂化型离子盐：[其中R1至R3分别独立地是卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基或氨基，可被取代；Q1是直链、氧原子、硫原子或较低的烷基链；T1是烷基或芳基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基；R4是烷基、烯丙基、芳基或芳基烷基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基或由通式[2]所示的基：（其中R5至R7分别独立地是卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基或氨基，可被取代；Q2是直链、氧原子、硫原子或较低的烷基链；T2是烷基或芳基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基；A3是一个对离子；m是0到4的整数；两个n各自独立地是0到5的整数）；A1和A2各自独立地是一个对离子；m和n与上述描述相同]，以及包含该离子盐的聚合引发剂或酸发生剂。
• N,N'-Bridged-bis(2-alkyl-2-hydroxyethylamine) dioxides
  申请人：Sterling Drug Inc.

  公开号：US04085144A1

  公开（公告）日：1978-04-18

  N,N'-Bridged-bis[(O and/or N-substituted)-2-alkyl-2-hydroxyethylamines] of the formula ##STR1## are prepared by condensing an epoxide of the formula ##STR2## and a diamine of the formula R'NH--X--NHR'. The products and dicarbanilates, acid-addition salts, N,N'-dioxides and N,N'-diammonium quaternary salts derived therefrom have antibacterial activity in vitro and are useful as antibacterial agents.

  公式为##STR1##的N,N'-桥联[(O和/或N取代)-2-烷基-2-羟乙胺]可通过将公式为##STR2##的环氧化物和公式为R'NH--X--NHR'的二胺缩合制备而成。由此派生的产物和二氢酰胺、酸加成盐、N,N'-二氧化物和N,N'-二铵季铵盐在体外具有抗菌活性，并可用作抗菌剂。
• N,N'-Bridged-bis[N,N'substituted-2-hydroxy alkaneammonium] salts
  申请人：Sterling Drug Inc.

  公开号：US04119668A1

  公开（公告）日：1978-10-10

  N,N'-Bridged-bis[(O and/or N-substituted)-2-alkyl-2-hydroxyethylamines] of the formula ##STR1## are prepared by condensing an epoxide of the formula ##STR2## and a diamine of the formula R'NH-X-NHR'. The products and dicarbanilates, acid-addition salts, N,N'-dioxides and N,N'-diammonium quaternary salts derived therefrom have antibacterial activity in vitro and are useful as antibacterial agents.

  公式为 ##STR1## 的N,N'-桥联的[(O和/或N取代)-2-烷基-2-羟乙胺]可通过将公式为 ##STR2## 的环氧化合物和公式为R'NH-X-NHR'的二胺进行缩合反应制备而成。由此得到的产物和二羰基酸酯、酸盐、N,N'-二氧化物和N,N'-二铵季铵盐具有体外抗菌活性，并可用作抗菌剂。