卑霉素 | 69787-80-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 卑霉素
• 中文别名: 阿维霉素
• 英文名称: Avilamycin C
• 英文别名: [(2R,3S,4R,6S)-6-[(2'R,3'S,3aR,4R,4'R,6S,7aR)-6-[(2S,3R,4R,5S,6R)-2-[(2R,3S,4S,5S,6S)-6-[(2R,3aS,3'aR,6S,6'R,7R,7'S,7aR,7'aR)-7'-hydroxy-7'-(1-hydroxyethyl)-6'-methyl-7-(2-methylpropanoyloxy)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,4'-6,7a-dihydro-3aH-[1,3]dioxolo[4,5-c]pyran]-6-yl]oxy-4-hydroxy-5-methoxy-2-(methoxymethyl)oxan-3-yl]oxy-3-hydroxy-5-methoxy-6-methyloxan-4-yl]oxy-4'-hydroxy-2',4,7a-trimethylspiro[3a,4,6,7-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2,6'-oxane]-3'-yl]oxy-4-hydroxy-2-methyloxan-3-yl] 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate
• CAS: 69787-80-0
• 化学式: C₆₁H₉₀Cl₂O₃₂
• 分子量: 1406.2
• InChiKey: AEIFATUAVHHRBC-GYPCSUJESA-N

物化性质

• 密度：
  1.50±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  95
• 可旋转键数：
  20
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  388
• 氢给体数：
  7
• 氢受体数：
  32

文献信息

• AVILAMYCIN-DERIVATE
  申请人：Combinature Biopharm AG

  公开号：EP1363924A1

  公开（公告）日：2003-11-26
• Avilamycin derivatives
  申请人：Combinature Biopharm AG

  公开号：US20040006026A1

  公开（公告）日：2004-01-08

  Avilamycin derivatives, gene technology biosynthesis processes for their production, medications containing these compounds, as well as the use of these compounds for the production of a active agent against infectious diseases, as well as nucleic acids, proteins, and gene clusters and corresponding cells that are connected to the production of these avilamycin derivatives are disclosed.
• [DE] AVILAMYCIN-DERIVATE<br/>[EN] AVILAMYCIN DERIVATIVES<br/>[FR] DERIVES D'AVILAMYCINE
  申请人：COMBINATURE BIOPHARM AG

  公开号：WO2002068436A1

  公开（公告）日：2002-09-06

  Die Erfindung betrifft Avilamycin-Derivate, gentechnologische biosynthetische Verfahren zu deren Herstellung, Arzneimittel enthaltend diese Verbindungen, sowie die Verwendung dieser Verbindungen zur Herstellung eines Arzneimittels gegen Infektionskrankheiten wie auch Nucleinsäuren, Proteine und Gencluster und entsprechende Zellen, die mit der Herstellung dieser Avilamycin-Derivate verbunden sind.