1-(2-phenylphenyl)-2-phenyl-1H-indole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1-(2-phenylphenyl)-2-phenyl-1H-indole
• 英文别名: N-biphenylyl-2-phenyl indole；2-phenyl-1-(2-phenylphenyl)indole
• 化学式: C₂₆H₁₉N
• 分子量: 345.444
• InChiKey: VEKNFDFAYYASQY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  4.9
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-phenyl-N-(2-(phenylethynyl)phenyl)aniline 在 palladium dichloride 、 (S)-(-)-5,5-双(二苯膦基)-4,4-双-1,3-苯并间二氧杂环戊烯 作用下， 以 乙醇 为溶剂， 以29%的产率得到
  参考文献：
  名称：

  Enantioselective synthesis of N–C axially chiral indoles through chiral palladium-catalyzed 5-endo-hydroaminocyclization

  摘要：

  In the presence of (R)-SEGPHOS-PdCl2 catalyst, 5-endo-hydroaminocyclization of various 2-(tert-butyl)-N-(2-ethynylphenyl)anilines proceeds enantioselectively to afford optically active N-C axially chiral N-(2-tert-butylphenyl)indole derivatives in good yields. The enantioselectivity depends strongly on the bulkiness of ortho-substituents and the electron density on the arylethynyl group, and it is explained by the dynamic axial chirality generated by the twisting of the aryl substituent. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2015.05.001

文献信息

• US3988437A
  申请人：——

  公开号：US3988437A

  公开（公告）日：1976-10-26
• [EN] LIGHT-EMITTING DEVICE, ORGANIC COMPOUND AND DISPLAY<br/>[FR] DISPOSITIF ELECTROLUMINESCENT, COMPOSE ORGANIQUE ET AFFICHAGE
  申请人：CANON KK

  公开号：WO2005051046A1

  公开（公告）日：2005-06-02

  There are provided an organic light-emitting device having a light output of a high emission efficiency and a high luminance and having high durability and a novel organic compound that enables the device to be attained. An organic compound of a long fluorescence lifetime represented by an organic compound having, in a molecule, at least one partial structure comprising an unsubstituted or substituted indole ring and at least one partial structure comprising an unsubstituted or substituted carbazole ring is used in an organic light-emitting device.
• Enantioselective synthesis of N–C axially chiral indoles through chiral palladium-catalyzed 5-endo-hydroaminocyclization
  作者：Yudai Morimoto、Satoshi Shimizu、Ayano Mokuya、Nobutaka Ototake、Akio Saito、Osamu Kitagawa

  DOI：10.1016/j.tet.2015.05.001

  日期：2016.8

  In the presence of (R)-SEGPHOS-PdCl2 catalyst, 5-endo-hydroaminocyclization of various 2-(tert-butyl)-N-(2-ethynylphenyl)anilines proceeds enantioselectively to afford optically active N-C axially chiral N-(2-tert-butylphenyl)indole derivatives in good yields. The enantioselectivity depends strongly on the bulkiness of ortho-substituents and the electron density on the arylethynyl group, and it is explained by the dynamic axial chirality generated by the twisting of the aryl substituent. (C) 2015 Elsevier Ltd. All rights reserved.