醋哌隆 | 807-31-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 醋哌隆
• 中文别名: 氟苯酰胺哌酮
• 英文名称: Aceperone
• 英文别名: N-[[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-phenylpiperidin-4-yl]methyl]acetamide
• CAS: 807-31-8
• 化学式: C₂₄H₂₉FN₂O₂
• 分子量: 396.5
• InChiKey: VDGZERMDPAAZEJ-UHFFFAOYSA-N

物化性质

• 熔点：
  97-100°

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  29
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Diagnostic/therapeutic agents
  申请人：Klaveness Jo

  公开号：US20050002865A1

  公开（公告）日：2005-01-06

  Targetable diagnostic and/or therapeutically active agents, e.g. ultrasound contrast agents, comprising a suspension in an aqueous carrier liquid of a reporter comprising gas-containing or gas-generating material, said agent being capable of forming at least two types of binding pairs with a target.

  可定位的诊断和/或治疗活性剂，例如超声对比剂，包括悬浮在水载体液中的报告物，该报告物包含含气体或生成气体的材料，该剂能够与目标形成至少两种结合对。
• Method for producing ketones from carboxylic acid anhydrides
  申请人：——

  公开号：US20040186321A1

  公开（公告）日：2004-09-23

  The invention relates to a method for producing ketones by reacting boric acid derivates with carbocylic acid anhydrides in the presence of a transition metal catalyst. The carboxylic acid anhydrides can either be used in isolated form or produced from carboxylic acids in a reaction mixture. This method enables the simple embodiment of a multitude of functionalised ketones in a single reaction step.

  本发明涉及一种方法，通过在过渡金属催化剂存在下，将硼酸衍生物与羧酸酐反应来生产酮。羧酸酐可以以分离形式使用，也可以从羧酸在反应混合物中制备而来。该方法使得在单个反应步骤中简单地实现多种官能团化的酮的实现。
• VERFAHREN ZUR HERSTELLUNG VON KETONEN AUS CARBONSÄUREANHYDRIDEN
  申请人：Studiengesellschaft Kohle mbH

  公开号：EP1389176A1

  公开（公告）日：2004-02-18
• Methods and devices for the treatment of ocular conditions
  申请人：deJuan Eugene

  公开号：US20060110428A1

  公开（公告）日：2006-05-25

  Featured is a method for instilling one or more bioactive agents into ocular tissue within an eye of a patient for the treatment of an ocular condition, the method comprising concurrently using at least two of the following bioactive agent delivery methods (A)-(C): (A) implanting a sustained release delivery device comprising one or more bioactive agents in a posterior region of the eye so that it delivers the one or more bioactive agents into the vitreous humor of the eye; (B) instilling (e.g., injecting or implanting) one or more bioactive agents subretinally; and (C) instilling (e.g., injecting or delivering by ocular iontophoresis) one or more bioactive agents into the vitreous humor of the eye.
• METHODS AND DEVICES FOR THE TREATMENT OF OCULAR CONDITIONS
  申请人：deJuan Eugene

  公开号：US20110159073A1

  公开（公告）日：2011-06-30

  Featured is a method for instilling one or more bioactive agents into ocular tissue within an eye of a patient for the treatment of an ocular condition, the method comprising concurrently using at least two of the following bioactive agent delivery methods (A)-(C): (A) implanting a sustained release delivery device comprising one or more bioactive agents in a posterior region of the eye so that it delivers the one or more bioactive agents into the vitreous humor of the eye; (B) instilling (e.g., injecting or implanting) one or more bioactive agents subretinally; and (C) instilling (e.g., injecting or delivering by ocular iontophoresis) one or more bioactive agents into the vitreous humor of the eye.