FX3QG8JQ24 | 374080-71-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: FX3QG8JQ24
• 英文别名: 2-[4-(4-chlorophenoxy)-3,5-dimethylpyrazol-1-yl]-4-pyridin-2-ylpyrimidine
• CAS: 374080-71-4
• 化学式: C₂₀H₁₆ClN₅O
• 分子量: 377.8
• InChiKey: TWJYGDKIIKYALT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  65.7
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS
  申请人：PureTech LYT, Inc.

  公开号：US20220001015A1

  公开（公告）日：2022-01-06

  The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.