(2R,3R,4S)-2-[(2R,4R,5R)-4,6-dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3R,4S)-2-[(2R,4R,5R)-4,6-dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
• 化学式: C₁₂H₁₉NO₁₆S₂
• 分子量: 497.4
• InChiKey: ZUXXVUFLLSQMNG-KDNOGOGDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.9
• 重原子数：
  31
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  293
• 氢给体数：
  8
• 氢受体数：
  17

文献信息

• Capillary Electrophoresis Method for Fine Structural Analysis of Enoxaparin Sodium
  申请人：Kang Jingwu

  公开号：US20130309655A1

  公开（公告）日：2013-11-21

  A capillary electrophoresis method for quantitatively analyzing characteristic oligosaccharide present in enoxaparin sodium is provided in this invention. The method may be used for quantitatively determining the contents of disaccharides, trisaccharides, tetrasaccharides and in particular oligosaccharides having a 1,6-anhydro ring, which are unique compounds for enoxaparin sodium, within an exhaustively digested enoxaparin sodium sample with a mixture of heparinase I, II, and III, so as to quantitatively determine the molar percentage of oligosaccharides having 1,6-anhydro ring in enoxaparin sodium. The method may be used for the pharmaceutical quality control of enoxaparin sodium during the manufacturing process.
• US9012229B2
  申请人：——

  公开号：US9012229B2

  公开（公告）日：2015-04-21