benzoyl benzenecarboperoxoate;(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: benzoyl benzenecarboperoxoate;(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
• 化学式: C51H77NO17
• 分子量: 976.2
• InChiKey: WIOGLCCGCVXFCT-YZPBMOCRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  69
• 可旋转键数：
  12
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  247
• 氢给体数：
  5
• 氢受体数：
  18

文献信息

• COMPOUND, COMPOSITION, AND METHOD FOR PROTECTING SKIN FROM HIGH ENERGY VISIBLE LIGHT
  申请人：PHOTOPROTECTIVE TECHNOLOGIES, INC.

  公开号：US20160317425A1

  公开（公告）日：2016-11-03

  A compound, composition, and method for the protection of skin from the harmful effects of radiation, and particularly the harmful effects of high energy visible (HEV) radiation, are disclosed. The compound is a melanin derivative that can be formulated into compositions containing the melanin derivative and a suitable carrier. The composition is topically applied to the skin to reduce the risk of photoaging and improve skin repair due to damage from radiation.

  揭示了一种用于保护皮肤免受辐射有害影响的化合物、组合物和方法，特别是高能可见光（HEV）辐射的有害影响。该化合物是一种黑色素衍生物，可配制成含有该黑色素衍生物和适当载体的组合物。该组合物局部应用于皮肤，以减少光老化的风险并改善由辐射造成的皮肤修复。
• Stable anhydrous compositions for topical delivery of active materials
  申请人：HELENE CURTIS, INC.

  公开号：EP0400546A1

  公开（公告）日：1990-12-05

  An anhydrous, topically-effective composition that resists phase separation and exhibits improved sensory properties comprising a topically-active compound, such as an astringent salt; a finely-divided silica; a suspending wax composition; and a suitable volatile liquid carrier vehicle, such as a volatile silicone or a volatile hydrocarbon. The anhydrous, topically-effective composition is useful in topical cosmetic and medicinal preparations, such as antiperspirants, sunscreens and topical drug products, and is especially useful in cosmetic and medicinal preparations wherein an insoluble topically-active compound is dispersed throughout a liquid phase.

  一种无水、局部有效的组合物，可防止相分离并显示出更好的感官特性，该组合物包含一种局部活性化合物，如一种收敛盐；一种细粒二氧化硅；一种悬浮蜡组合物；以及一种合适的挥发性液体载体，如一种挥发性硅酮或一种挥发性烃。这种无水、局部有效的组合物适用于局部化妆品和药物制剂，如止汗剂、防晒霜和局部药物产品，尤其适用于在液相中分散不溶性局部活性化合物的化妆品和药物制剂。
• Compound, composition, and method for protecting skin from high energy visible light
  申请人：Photoprotective Technologies, Inc.

  公开号：US10357124B2

  公开（公告）日：2019-07-23

  A compound, composition, and method for the protection of skin from the harmful effects of radiation, and particularly the harmful effects of high energy visible (HEV) radiation, are disclosed. The compound is a melanin derivative that can be formulated into compositions containing the melanin derivative and a suitable carrier. The composition is topically applied to the skin to reduce the risk of photoaging and improve skin repair due to damage from radiation.

  本发明公开了一种化合物、组合物和方法，用于保护皮肤免受辐射的有害影响，特别是高能可见辐射（HEV）的有害影响。该化合物是一种黑色素衍生物，可配制成含有黑色素衍生物和适当载体的组合物。将该组合物局部涂抹于皮肤，可降低光老化的风险，并改善因辐射损伤造成的皮肤修复。
• Sustained release compositions and controlled delivery method
  申请人：Sojka Milan

  公开号：US20050002996A1

  公开（公告）日：2005-01-06

  A sustained release composition comprising cellulose fibers, an active agent, and an optional release retardant is disclosed. The composition has an improved ability to stabilize and release the active agent over an extended time period.

  本发明公开了一种由纤维素纤维、活性剂和任选缓释剂组成的缓释组合物。该组合物在较长时间内稳定和释放活性剂的能力有所提高。
• IMPROVED CONTROLLED RELEASE COMPOSITIONS
  申请人：AMCOL INTERNATIONAL CORPORATION

  公开号：EP1140033B1

  公开（公告）日：2005-10-12