Methyl 3-[3-[(2,6-dichlorophenyl)methoxy]phenyl]-3-oxopropanoate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methyl 3-[3-[(2,6-dichlorophenyl)methoxy]phenyl]-3-oxopropanoate
• 化学式: C₁₇H₁₄Cl₂O₄
• 分子量: 353.2
• InChiKey: XTIJRXSYFFFCBD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
  申请人：Wellstat Therapeutics Corporation

  公开号：EP1556085A2

  公开（公告）日：2005-07-27
• Compounds for the treatment of metabolic disorders
  申请人：Hodge L. Kirvin

  公开号：US20060035970A1

  公开（公告）日：2006-02-16

  Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
• US7645772B2
  申请人：——

  公开号：US7645772B2

  公开（公告）日：2010-01-12
• [EN] FATTY ACID SYNTHASE INHIBITORS<br/>[FR] INHIBITEURS DE LA SYNTHASE D'ACIDES GRAS
  申请人：SMITHKLINE BEECHAM CORP

  公开号：WO2002002119A1

  公开（公告）日：2002-01-10

  This invention relates to the use of compounds as inhibitors of the fatty acid synthase FabH.
• [EN] COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS<br/>[FR] COMPOSES DESTINES AU TRAITEMENT DE TROUBLES METABOLIQUES
  申请人：WELLSTAT THERAPEUTICS CORP

  公开号：WO2004041165A2

  公开（公告）日：2004-05-21

  Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.