1-allyl-2-methoxycyclohexanol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-allyl-2-methoxycyclohexanol
• 英文别名: Cyclohexanol, 2-methoxy-1-(2-propenyl)-；2-methoxy-1-prop-2-enylcyclohexan-1-ol
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: UKWAWZUWQVKSBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-甲氧基环己酮 、 3-溴丙烯 在 indium 作用下， 以 水 为溶剂， 反应 8.0h， 以93%的产率得到1-allyl-2-methoxycyclohexanol
  参考文献：
  名称：

  Allylation of cyclohexanones in aqueous media and influence of facial amphiphilic fructopyranosides

  摘要：

  The indium-catalyzed allylation reaction was performed in good yields and short reaction time with various cyclohexanones in water. Aqueous facial amphiphilic carbohydrates solutions were also screened for their potency to modify the stereochemical outcome of the reaction. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.07.028

文献信息

• [EN] PRODUCTION OF 3-ALKYLPHENOLS AND USES THEREOF<br/>[FR] PRODUCTION DE 3-ALKYLPHÉNOLS ET LEURS UTILISATIONS
  申请人：UNIV LEUVEN KATH

  公开号：WO2016187678A1

  公开（公告）日：2016-12-01

  In general the present invention concerns a method for conversion of particular 4-alkyl-2- hydroxyphenols and 4-alkyl-2-alkoxyphenols into 3-alkylphenols. More specifically, this invention relates to a novel process of selectively forming meta-alkyl phenols of various alkylphenols, such as for instance converting the fraction of 4-alkyl-2-hydroxyphenols and 4- alkyl-2-alkoxyphenols into high yields of 3-alkylphenols.

  一般来说，本发明涉及一种将特定的4-烷基-2-羟基苯酚和4-烷基-2-烷氧基苯酚转化为3-烷基苯酚的方法。更具体地说，本发明涉及一种新颖的选择性形成各种烷基苯酚的间位烷基苯酚的方法，例如将4-烷基-2-羟基苯酚和4-烷基-2-烷氧基苯酚的部分转化为高收率的3-烷基苯酚。
• Samarium-mediated Barbier reaction of carbonyl compounds
  作者：Manas K Basu、Bimal K Banik

  DOI：10.1016/s0040-4039(00)01961-4

  日期：2001.1

  Samarium metal in the presence of catalytic amounts of iodine was found to be effective for the Barbier reaction of carbonyl compounds. (C) 2000 Elsevier Science Ltd. All rights reserved.
• PRODUCTION OF 3-ALKYLPHENOLS AND USES THEREOF
  申请人：Katholieke Universiteit Leuven

  公开号：EP3303276A1

  公开（公告）日：2018-04-11
• Allylation of cyclohexanones in aqueous media and influence of facial amphiphilic fructopyranosides
  作者：Ana Bellomo、Richard Daniellou、Daniel Plusquellec

  DOI：10.1016/j.tetlet.2010.07.028

  日期：2010.9

  The indium-catalyzed allylation reaction was performed in good yields and short reaction time with various cyclohexanones in water. Aqueous facial amphiphilic carbohydrates solutions were also screened for their potency to modify the stereochemical outcome of the reaction. (C) 2010 Elsevier Ltd. All rights reserved.