1-(1-Hydroxypropoxy)propan-1-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(1-Hydroxypropoxy)propan-1-ol
• 化学式: C₆H₁₄O₃
• 分子量: 134.17
• InChiKey: QYSXYAURTRCDJU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
  申请人：Scott Ian L.

  公开号：US20100093865A1

  公开（公告）日：2010-04-15

  Provided are sulphur-linked compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.

  提供的是硫连接化合物、其药物组合物以及使用所述化合物和组合物治疗眼科疾病和障碍的方法，例如年龄相关的黄斑变性和斯达加特病。
• AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
  申请人：Acucela, Inc.

  公开号：US20160193181A1

  公开（公告）日：2016-07-07

  Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.

  提供的是胺衍生物化合物、其药物组合物，以及使用所述化合物和组合物治疗眼科疾病和障碍的方法，例如年龄相关的黄斑变性和斯达格特病。
• Novel dimercaptoamides, compositions comprising them as reducing agents, and processes for permanently reshaping keratin fibers therewith
  申请人：Philippe Michel

  公开号：US20060013784A1

  公开（公告）日：2006-01-19

  The present disclosure relates to specific dimercaptoamides, reducing compositions for permanently reshaping keratin fibers comprising the dimercaptoamides, for instance, human keratin fibers such as the hair; and processes for reshaping keratin fibers comprising the application of said reducing compositions. The present disclosure also relates to processes for preparing the dimercaptoamides.

  本公开涉及特定的二硫代酰胺，用于永久性重塑角蛋白纤维的还原组合物，例如人类角蛋白纤维，如头发；以及包括应用所述还原组合物在内的重塑角蛋白纤维的过程。本公开还涉及制备二硫代酰胺的过程。
• [EN] ANESTHETIC COMPOUNDS AND RELATED METHODS OF USE<br/>[FR] COMPOSÉS ANESTHÉSIQUES ET PROCÉDÉS D'UTILISATION AFFÉRENTS
  申请人：GEN HOSPITAL CORP

  公开号：WO2013106717A1

  公开（公告）日：2013-07-18

  Provided herein are compounds according to formula (I): Provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.

  本文提供了符合以下式(I)的化合物。本文还提供了一种包含符合式(I)的化合物和药用可接受载体的药物组合物，以及通过给予受试者这种药物组合物来提供麻醉的方法。
• [EN] PHARMACEUTICAL COMPOSITIONS<br/>[FR] COMPOSITIONS PHARMACEUTIQUES
  申请人：GENZYME CORP

  公开号：WO2009154747A1

  公开（公告）日：2009-12-23

  This invention relates to crosslinked amine-containing polymers for binding compounds or ions, and more specifically relates to pharmaceutically acceptable compositions for binding compounds or ions that include crosslinked amine-containing polymers. The pharmaceutically acceptable composition includes, for example, crosslinked polyamine particles, or pharmaceutically acceptable salts thereof, having a particle size distribution wherein greater than 10 vol.% of the particles have a particle size greater than 500 μm.

  这项发明涉及交联胺含有聚合物用于结合化合物或离子，更具体地涉及用于结合化合物或离子的药用可接受组合物，其中包括交联胺含有聚合物。药用可接受组合物包括例如交联聚胺颗粒或其药用可接受盐，具有粒径分布，其中大于10体积%的颗粒具有大于500μm的粒径。