(3R)-2,2,3-trimethylpentan-3-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3R)-2,2,3-trimethylpentan-3-ol
• 化学式: C₈H₁₈O
• 分子量: 130.23
• InChiKey: KLIHWYNSISMOMR-MRVPVSSYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOLS AND CHIRAL AMINES
  申请人：University College Dublin

  公开号：US20170204036A1

  公开（公告）日：2017-07-20

  A process for the stereoselective preparation of a chiral alcohol or a chiral amine, the process comprising reacting a first prochiral reactant selected from the group consisting of a ketone, an aldehyde, and an imine, with a second reactant comprising a Grignard reagent, in the presence of a chiral trans-diamine of formula (1) as defined herein: Also provided is the use of the chiral trans-diamine of formula (1) in a Grignard reaction and the chiral trans-diamines per se.