methyl-(5-pentafluoroethyl-pyridin-2-yl)-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: methyl-(5-pentafluoroethyl-pyridin-2-yl)-amine
• 英文别名: Methyl-(5-pentafluoroethyl-pyridine-2-yl)-amine；N-methyl-5-(1,1,2,2,2-pentafluoroethyl)pyridin-2-amine
• 化学式: C₈H₇F₅N₂
• 分子量: 226.149
• InChiKey: WCPGHPMIGOLTRT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  24.9
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  methyl-(5-pentafluoroethyl-pyridin-2-yl)-amine 在 ammonium hydroxide 、 N-溴代丁二酰亚胺(NBS) 、 copper(II) acetylacetonate 、 caesium carbonate 、 乙酰丙酮 作用下， 以 N-甲基吡咯烷酮 、 水 、 乙腈 为溶剂， 反应 23.0h， 生成 N2-甲基-5-(全氟乙基)吡啶-2,3-二胺
  参考文献：
  名称：

  EP2865672

  摘要：

  公开号：
• 作为产物：
  描述：

  2-氯-5-碘吡啶 在 copper(l) iodide 作用下， 以 N-甲基吡咯烷酮 、 乙醇 、 对二甲苯 为溶剂， 反应 6.0h， 生成 methyl-(5-pentafluoroethyl-pyridin-2-yl)-amine
  参考文献：
  名称：

  [EN] CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYLPYRIDINE DERIVATIVES
  [FR] DÉRIVÉS D'ÉTHYLSULFONYLPYRIDINE À SUBSTITUTION CYCLOPROPYLE- (HÉTÉRO)ARYLE

  摘要：

  The present invention relates to cyclopropyl-(hetero)aryl substituted ethylsulphonyl-pyridine derivatives of formula (I),wherein the variables are as defined in the description and in the claims, which can be used as antiparasitic agents for the treatment, prevention and/or control of parasitic infections and/or infestations in animals.

  公开号：

  WO2023036934A1

文献信息

• [EN] FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF<br/>[FR] COMPOSÉ HÉTÉROCYCLIQUE FUSIONNÉ ET SON UTILISATION POUR LA LUTTE CONTRE LES RAVAGEURS
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2012086848A1

  公开（公告）日：2012-06-28

  A fused heterocyclic compound the formula (1) : wherein A1 represents -NR8-, and the like; A2 represents a nitrogen atom, and the like; A3 represents a nitrogen atom, and the like; R1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R2, R3, R4, and R5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R6 and R7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.

  一种融合的杂环化合物，其化学式（1）：其中A1代表-NR8-等；A2代表一个氮原子等；A3代表一个氮原子等；R1代表一个C1-C6链烃基，可选地具有来自X组的一个或多个原子或基团等；R2、R3、R4和R5相同或不同，独立地代表一个C1-C6链烃基，可选地具有一个或多个卤素原子等；R6和R7相同或不同，独立地代表一个C1-C6链烃基，可选地具有来自X组的一个或多个原子或基团等；R8代表一个C1-C6链烃基，可选地具有来自W组的一个或多个原子或基团等；n代表0、1或2。该化合物具有优异的控制害虫活性。
• Fused heterocyclic compound and use thereof for pest control
  申请人：Takyo Hayato

  公开号：US08853238B2

  公开（公告）日：2014-10-07

  A fused heterocyclic compound the formula (1): wherein A1 represents —NR8—, and the like; A2 represents a nitrogen atom, and the like; A3 represents a nitrogen atom, and the like; R1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R2, R3, R4, and R5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R6 and R7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.

  一种融合的杂环化合物，化学式（1）：其中A1代表—NR8—等；A2代表氮原子等；A3代表氮原子等；R1代表C1-C6链烃基，可选含有一种或多种来自X族的原子或基团等；R2、R3、R4和R5相同或不同，分别独立地代表C1-C6链烃基，可选含有一种或多种卤素原子等；R6和R7相同或不同，分别独立地代表C1-C6链烃基，可选含有一种或多种来自X族的原子或基团等；R8代表C1-C6链烃基，可选含有一种或多种来自W族的原子或基团等；n代表0、1或2。该化合物具有优异的控制害虫活性。
• FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF
  申请人：Takyo Hayato

  公开号：US20140018373A1

  公开（公告）日：2014-01-16

  A fused heterocyclic compound the formula (1): wherein A 1 represents —NR 8 —, and the like; A 2 represents a nitrogen atom, and the like; A 3 represents a nitrogen atom, and the like; R 1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R 2 , R 3 , R 4 , and R 5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R 6 and R 7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R 8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.

  一种融合的杂环化合物，化学式（1）：其中A1代表—NR8—等；A2代表氮原子等；A3代表氮原子等；R1代表C1-C6链烃基，可选含有一种或多种来自X组的原子或基团等；R2、R3、R4和R5相同或不同，分别独立地代表可选含有一种或多种卤素原子等的C1-C6链烃基；R6和R7相同或不同，分别独立地代表可选含有一种或多种来自X组的原子或基团等的C1-C6链烃基；R8代表可选含有一种或多种来自W组的原子或基团等的C1-C6链烃基；n代表0、1或2。该化合物具有优异的杀虫活性。
• Fused heterocyclic compound
  申请人：Sumitomo Chemical Company, Limited

  公开号：US09156838B2

  公开（公告）日：2015-10-13

  This fused heterocyclic compound represented in formula (1) has excellent effectiveness in pest control. In the formula, A1 represents —NR4—, etc.; A2 represents a nitrogen atom, etc.; R1 represents an ethyl group, a cyclopropyl group, or a cyclopropylmethyl group; R2 represents —S(O)mR6 or —C(R7)(CF3)2; R4 represents a C1-C6 alkyl group optionally having one or more halogen atoms; R6 represents a C1-C6 haloalkyl group; R7 represents a fluorine atom or a chlorine atom, and m and n each represents 0, 1 or 2.

  在式(1)中表示的这种融合的杂环化合物在害虫控制方面具有出色的效果。在公式中，A1表示- NR4-等; A2表示氮原子等; R1表示乙基基团，环丙基基团或环丙甲基基团; R2表示-S（O）mR6或-C（R7）（CF3）2; R4表示C1-C6烷基基团，可选择地具有一个或多个卤素原子; R6表示C1-C6卤代烷基基团; R7表示氟原子或氯原子，m和n各表示0、1或2。
• FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20140364444A1

  公开（公告）日：2014-12-11

  A fused heterocyclic compound the formula (1): wherein A 1 represents —NR 8 —, and the like; A 2 represents a nitrogen atom, and the like; A 3 represents a nitrogen atom, and the like; R 1 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R 2 , R 3 , R 4 , and R 5 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more halogen atoms, and the like; R 6 and R 7 are same or different and represent independently a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group X, and the like; R 8 represents a C1-C6 chain hydrocarbon group optionally having one or more atoms or groups selected from Group W, and the like; n represents 0, 1 or 2. The compound has an excellent activity of controlling pests.

  一种融合的杂环化合物，化学式（1）：其中A1代表- NR8-等；A2代表氮原子等；A3代表氮原子等；R1代表C1-C6链烃基，可选地具有来自X族的一个或多个原子或基团等；R2，R3，R4和R5相同或不同，分别独立地代表C1-C6链烃基，可选地具有一个或多个卤素原子等；R6和R7相同或不同，分别独立地代表C1-C6链烃基，可选地具有来自X族的一个或多个原子或基团等；R8代表C1-C6链烃基，可选地具有来自W族的一个或多个原子或基团等；n代表0、1或2。该化合物具有优异的控制害虫活性。