4-thiocyanato-2-butanol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-thiocyanato-2-butanol
• 英文别名: 3-thiocyano-2-butanol；1-Thiocyano-3-butanol；3-hydroxybutyl thiocyanate
• 化学式: C₅H₉NOS
• 分子量: 131.199
• InChiKey: JVIDMXBLENGMLG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  69.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-thiocyanato-2-butanol 在 三乙胺 、 三氯化磷 作用下， 以 乙醚 为溶剂， 生成 2-(1-methyl-3-thiocyanatopropoxy)-4,5-dimethyl-1,3,2-dioxaphospholane
  参考文献：
  名称：

  Reactions of 1,3,2-dioxaphospholane derivatives with thiocyanatoalcohols

  摘要：

  The reactions of 2-dimethylamino-, 2-methoxy-, 2-chloro-4,5-dimethyl-1,3,2-dioxaphospholanes with 4-thiocyanato-2-butanol in all cases yield 2-(1-methyl-3-thiocyanatopropoxy)4,5-dimethyl-1,3,2-dioxaphospholane. The latter reacts with elemental sulfur to form the corresponding thiophosphate.

  DOI：

  10.1007/bf00698895

文献信息

• Transformations of thiocyanoalkyl phosphites and amidophosphites
  作者：O. N. Nuretdinova、V. G. Novikova、L. B. Troitskaya

  DOI：10.1007/bf00863384

  日期：1992.11

  The ratio of the alkoxy and dialkylamido groups in thiocyanoalkyl phosphites determines the structure of the transformation products of these compounds.
• Reaction of tetraethyldiamidochlorophosphite with thiocyanoalcohols
  作者：O. N. Nuretdinova、V. G. Novikova

  DOI：10.1007/bf00863386

  日期：1992.11

  The reaction of tetraethyldiamidochlorophosphite with 1-thiocyano-3-butanol in the presence of triethylamine at low temperature leads to the formation of tetraethyldiamidocyanophosphine.
• Reactions ofO-methyl tetramethyldiamidophosphite with halo- and thiocyanoalcohols
  作者：O. N. Nuretdinova、F. F. Guseva、V. G. Novikova

  DOI：10.1007/bf00699159

  日期：1994.1

  The reaction of O-methyl tetramethyldiamidophosphite with 5-bromopropanol or 3-bromo-2-butanol occurs with the liberation of dimethylamine and results in mixed phosphites. The reaction of O-methyl tetramethyldiamidophosphite with 3-thiocyano-2-butanol proceeds with the participation of the sulfur atom of the thiocyano group and formation of S-(3-hydroxybutyl) tetramethyldiamidothiophosphate.
• Reactions of some acid phosphates and thiophosphites with thiocyanatoalcohols
  作者：O. N. Nuretdinova

  DOI：10.1007/bf01433767

  日期：1996.1

  Thiocyanatoalcohols react with some acid alkylene glycol phosphites and thiophosphites in the presence of Et(3)N to give the corresponding hydroxyalkyl alkylene glycol thiophosphates or hydroxyalkyl dithiophosphates. The structure of the latter compounds determines their subsequent conversions.
• Reactions of 1,3,2-dioxaphospholane derivatives with thiocyanatoalcohols
  作者：O. N. Nuretdinova、V. G. Novikova

  DOI：10.1007/bf00698895

  日期：1993.12

  The reactions of 2-dimethylamino-, 2-methoxy-, 2-chloro-4,5-dimethyl-1,3,2-dioxaphospholanes with 4-thiocyanato-2-butanol in all cases yield 2-(1-methyl-3-thiocyanatopropoxy)4,5-dimethyl-1,3,2-dioxaphospholane. The latter reacts with elemental sulfur to form the corresponding thiophosphate.