5-(ethyl-methyl-amino)-pentan-2-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-(ethyl-methyl-amino)-pentan-2-one
• 英文别名: 5-(Aethyl-methyl-amino)-pentan-2-on；2-Pentanone, 5-(ethylmethylamino)-；5-[ethyl(methyl)amino]pentan-2-one
• 化学式: C₈H₁₇NO
• 分子量: 143.229
• InChiKey: UFJCHNNTOOVVCC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  5-溴-2-戊酮 、 N-乙基甲基胺 生成 5-(ethyl-methyl-amino)-pentan-2-one
  参考文献：
  名称：

  2-甲氧基-6-氯-9-（N-取代的氨基）-啶; 衍生自环状仲胺的化合物。

  摘要：

  DOI：

  10.1021/ja01214a012

文献信息

• [EN] PREPARATION OF 3-AMINOALKYL-SUBSTITUTED INDOLE DERIVATIVES FROM PHENYLHYDRAZINES AND AMINOKETONES<br/>[FR] PREPARATION DE DERIVES D'INDOLE A SUBSTITUTION 3-AMINOALKYLE A PARTIR DE PHENYLHYDRAZINES ET D'AMINOCETONES
  申请人：SUVEN LIFE SCIENCES LTD

  公开号：WO2004041781A1

  公开（公告）日：2004-05-21

  The present invention relates to a process for the preparation of indole derivatives, particularly those, which are useful as pharmaceutical intermediates. The process involves formation of hydrazone derivative between a phenyl hydrazine and a ketone amine, followed by cyclisation to give desired 2,3-substituted indole derivative in the presence of acid catalyst.

  本发明涉及一种制备吲哚衍生物的方法，特别是那些作为药物中间体有用的衍生物。该方法涉及在酸催化剂存在下，通过苯基肼和酮胺之间的缩醛衍生物的形成，然后进行环化反应，得到所需的2,3-取代吲哚衍生物。
• 9-amino-alkyl-amino-substituted acridine derivatives
  申请人：LILLY CO ELI

  公开号：US02424061A1

  公开（公告）日：1947-07-15
• COMPOSTABLE OLEFIN POLYMER COMPOSITIONS
  申请人：BIOtech Products, LLC

  公开号：EP2262855A1

  公开（公告）日：2010-12-22
• Compostable Olefin Polymer Compositions, Composites and Landfill Biodegradation
  申请人：Grossman Richard F.

  公开号：US20090253324A1

  公开（公告）日：2009-10-08

  Compositions of olefin polymers such as those derived from monomers of ethylene, propylene, diene and copolymers or terpolymers thereof, are rendered compostable by a monomeric adduct of an organotitanate or zirconate as a prodegradant. Olefin polymer sheets and composites are compostable in landfills.
• Anaerobically Compostable Polymeric Compositions, Articles and Landfill Biodegradation
  申请人：Grossman Richard F.

  公开号：US20090275111A1

  公开（公告）日：2009-11-05

  Compostable hydrocarbon polymers, composites, and articles anaerobically biodegrade in landfills in a relatively short time. Composite polymeric articles and sheets such as indoor or outdoor signs, billboards, banners, images, protective barriers, backdrops and wall coverings have very useful service durations and yet are landfill biodegradable.