HONTA

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: HONTA
• 英文别名: N,N,N',N',N'',N''-hexa-n-octylnitrilotriacetamide；2-[bis[2-(dioctylamino)-2-oxoethyl]amino]-N,N-dioctylacetamide
• 化学式: C₅₄H₁₀₈N₄O₃
• 分子量: 861.477
• InChiKey: YTTXOOIRNCYALH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  19.4
• 重原子数：
  61
• 可旋转键数：
  48
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  64.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  HONTA 、 硝酸 、 在 水 作用下， 以 十二烷 为溶剂， 生成 [Pu(NO₃)₄-(N,N,N',N',N'',N''-hexa(n-octyl)nitrilotriacetamide)₂]
  参考文献：
  名称：

  三足酰胺配体间隔长度对铀 (VI) 和钚 (IV) 络合的作用：合成、溶剂萃取、液膜传输和理论研究

  摘要：

  几种锕系和镧系离子的液液萃取，即。, U( VI ), Pu( IV ), Am( III ) 和 Eu( III ) 采用N , N , N ', N ', N '', N ' ' -hexan -在 90%正十二烷 + 10% 异癸醇中的辛基次氮基三丙酰胺 (HONTP) 。观察到在 0.5 M HNO 3下金属离子萃取的趋势是 Pu( IV ) > U( VI ) > Eu( III ) ∼ Am( III）。在 90%正十二烷 + 10% 异癸醇中使用 0.08 M HONTP 在 pH 2下观察到 U( VI ) 的高分配比。分别使用 0.5 M HNO 3 + 0.5 M 草酸和 1 M Na 2 CO 3对 Pu( IV ) 和 U( VI ) 的反萃取研究表明，这两种金属离子从负载有机相。斜率分析表明，在 3 M HNO 3下，Pu( IV ) 与 HONTP形成了化学计量较低的复合物，而

  DOI：

  10.1039/d2nj03354b
• 作为产物：
  描述：

  2-chloro-N,N-dioctylacetamide 在 palladium 10% on activated carbon 、 氢气 、 potassium carbonate 、 potassium iodide 作用下， 以 乙醇 、 乙腈 为溶剂， 生成 HONTA
  参考文献：
  名称：

  Synthesis and Am/Eu extraction of novel TODGA derivatives

  摘要：

  Various ligands with structural modifications of the N,N,N',N'-tetraoctyl-3-oxapentanediamide (TODGA) skeleton were synthesised in good yields. These modifications include (1) the increase in chain length from one carbon to two carbons between the central ether oxygen atom and the amide moieties, (2) the addition of substituents on the carbon between the central oxygen atom and the amide moieties on one and both sides of the central oxygen, (3) the replacement of the central oxygen by a (substituted) nitrogen atom and (4) synthesis of a rigidified glycolamide. The effect of the structural modifications on their extraction behaviours toward Am(III) and Eu(III) at various nitric acid concentrations was studied. In most of the cases, the extraction does not exceed that of TODGA in the entire acidity range of 0.001-4mol/l HNO3. The extraction behaviour of monomethyl-TODGA derivative 10a resembles that of TODGA at high nitric acid concentrations. However, at lower acidities, its D values are much lower, which is beneficial for possible back-extraction steps. The aza-tripodal ligands 18a,b show reverse extraction properties compared to TODGA as far as the pH influence is concerned: at pH 2, the DAm values are 49.9 and 3.1, the DEu values are 5.9 and 0.2, and the SAm/Eu values are 8 and 11, respectively.

  DOI：

  10.1080/10610278.2010.506553

文献信息

• Extraction and Complexation Investigation of Palladium(II) by a Nitrilotriacetate-Derived Triamide Ligand
  作者：Xueyu Wang、Lianjun Song、Long Li、Zhuang Wang、Qiuju Li、Lanlan He、Xuanhao Huang、Songdong Ding

  DOI：10.1021/acs.inorgchem.2c00675

  日期：2022.8.29

  recovery of the fission product palladium from high-level liquid waste are conducive not only to reducing its hazards to the public health and environment but also to alleviate the pressure on the increasing demand for natural palladium. Herein, the Pd2+ extraction in an HNO3 solution with a nitrilotriacetate-derived triamide ligand NTAamide(n-Oct) and the complexation between them were investigated

  从高放废液中有效、选择性地分离回收裂变产物钯，不仅有利于降低其对公众健康和环境的危害，也有利于缓解天然钯需求增加的压力。在此，研究了HNO 3溶液中的Pd 2+萃取与次氮基三乙酸酯衍生的三酰胺配体NTAamide( n- Oct)及其之间的络合。NTAamide( n- Oct)使用正辛醇作为稀释剂，对 Pd 2+表现出优异的选择性、强萃取性和高负载能力萃取。结合单晶X射线衍射、傅里叶变换红外光谱、电喷雾电离质谱、微量热滴定和斜率分析结果，确定萃取的配合物为[PdL 2 ](NO 3 ) 2和[PdL 2 ][Pd(NO 3 ) 4 ]（其中 L 表示 NTAamide 配体）分别在 0.10 和 3.0 mol/L HNO 3溶液中。萃取模型与HNO 3溶液中Pd 2+的溶剂化状态密切相关。提出并讨论了离子对提取模型。
• A H-Bonding and Electrostatic Interaction Combined Strategy for TcO₄^– Separation by a Nitrotriacetate-Derived Amine–Amide Extractant
  作者：Xueyu Wang、Songdong Ding、Zhipeng Wang、Lianjun Song、Xiuying Yang、Qian Xiao、Haowei Xu、Junli Wang、Zhen Shen、Hui Wang

  DOI：10.1021/acs.inorgchem.1c00111

  日期：2021.8.2