四甲基癸二胺 | 13424-83-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 四甲基癸二胺
• 英文名称: Tetramethyl-sebacamid
• 英文别名: Tetramethylsebacamide；N,N,N',N'-tetramethyldecanediamide
• CAS: 13424-83-4
• 化学式: C₁₄H₂₈N₂O₂
• 分子量: 256.389
• InChiKey: JMUQDPZSXKUXTI-UHFFFAOYSA-N

物化性质

• 沸点：
  399.63°C (rough estimate)
• 密度：
  0.9807 (rough estimate)
• 溶解度：
  >38.5 [ug/mL]

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2924199090

反应信息

• 作为反应物：
  描述：

  N,N′-六亚甲基双乙酰胺 、 四甲基癸二胺 生成 N,N-二甲基乙酰胺 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Amide interchange reactions

  摘要：

  Abstract(1) Sebacamide and N,N′‐diacetylhexamethylenediamine interchange to produce acetamide and polyhexamethylene sebacamide. (2) The rate is proportional to the concentrations of the two reacting species and to the square root of carboxyl group concentration. (3) The rate increases with increasing concentration of water. Reagents which had been held in the molten state under high vacuum were still capable of reaction. (4) N‐Substitution decreases the rate constant; the isobutyl group is more effective than methyl in this respect. (5) As an indication of the amount of interchange occurring during a typical polymerization, it is computed that at least 42% of the amide links interchange during the 66 nylon synthesis. This means that it is not feasible to make nonrandom copolyamides by polymerizing together low molecular weight homopolyamides. Interchange does provide for the production of nonrandom copolymers from two or more high molecular weight homopolyamides.

  DOI：

  10.1002/pol.1952.120080404
• 作为产物：
  描述：

  癸二酰氯 、 N,N-二甲基甲酰胺 反应 12.0h， 以95%的产率得到四甲基癸二胺
  参考文献：
  名称：

  N,N-Dimethylamination of Acid Chlorides with Dmf

  摘要：

  A solution of acid chlorides 3a-g in DMF solvent was refluxed to give N,N-dimethylamides 4a-f and 5g in excellent yields.

  DOI：

  10.1080/00397910008087045

文献信息

• p-(p-Aminophenyl)-benzenesulfonamide and Derivatives
  作者：I. F. Halverstadt、W. D. Kumler

  DOI：10.1021/ja01847a506

  日期：1941.2
• Amide interchange reactions
  作者：L. F. Beste、R. C. Houtz

  DOI：10.1002/pol.1952.120080404

  日期：1952.4

  Abstract(1) Sebacamide and N,N′‐diacetylhexamethylenediamine interchange to produce acetamide and polyhexamethylene sebacamide. (2) The rate is proportional to the concentrations of the two reacting species and to the square root of carboxyl group concentration. (3) The rate increases with increasing concentration of water. Reagents which had been held in the molten state under high vacuum were still capable of reaction. (4) N‐Substitution decreases the rate constant; the isobutyl group is more effective than methyl in this respect. (5) As an indication of the amount of interchange occurring during a typical polymerization, it is computed that at least 42% of the amide links interchange during the 66 nylon synthesis. This means that it is not feasible to make nonrandom copolyamides by polymerizing together low molecular weight homopolyamides. Interchange does provide for the production of nonrandom copolymers from two or more high molecular weight homopolyamides.
• <i>N,N</i>-Dimethylamination of Acid Chlorides with Dmf
  作者：Woo Song Lee、Ki Hun Park、Yong-Jin Yoon

  DOI：10.1080/00397910008087045

  日期：2000.12

  A solution of acid chlorides 3a-g in DMF solvent was refluxed to give N,N-dimethylamides 4a-f and 5g in excellent yields.