地衣酸钠 | 34769-44-3

• 物质功能分类: 生物化工 - 提取物 - 植物提取物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 地衣酸钠
• 中文别名: 2,6-二乙酰基-7,9-二羟基-8,9b-二甲基二苯并呋喃-1,3(2H,9bH)-二酮单钠盐；(+)-松萝酸钠；松萝酸钠盐
• 英文名称: Usnicacidsodium
• CAS: 34769-44-3
• 化学式: C18H16NaO7
• 分子量: 367.3
• InChiKey: YGZOLUSJFYDOMD-UHFFFAOYSA-N

物化性质

• 熔点：
  >204°C (dec.)
• 溶解度：
  可溶于DMSO（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  1.12
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  118
• 氢给体数：
  2
• 氢受体数：
  7

制备方法与用途

用途

松萝酸钠可用作抗菌剂和抗真菌剂，常用于化妆品和面部应用化学品中。

化学性质

松萝酸钠呈浅黄色结晶状，可溶于甲醇、乙醇及DMSO等有机溶剂，来源于松萝。

它具有显著的抑菌作用。

文献信息

• [EN] DIBENZOFURAN DERIVATIVES WITH ANTIBACTERIAL AND WOUND-HEALING ACTIVITY<br/>[FR] DÉRIVÉS DE DIBENZOFURANNE À ACTIVITÉ ANTIBACTÉRIENNE ET DE CICATRISATION DE PLAIES
  申请人：UNIV DEGLI STUDI MILANO

  公开号：WO2013189950A1

  公开（公告）日：2013-12-27

  Disclosed are dibenzofuran derivatives of usnic acid, compositions thereof and use thereof in dermatological or cosmetic formularions with antimicrobial, regenerative and anti-aging purposes.

  揭示了乌司酸的二苯并呋喃衍生物，以及它们的组合物，并将其用于具有抗菌、再生和抗衰老作用的皮肤科或化妆品配方中。
• PHARMACEUTICAL DISINFECTANTS COMPRISING USNIC ACID AND ESSENTIAL OILS
  申请人：AD "ZDRAVLJE"

  公开号：EP1294373A1

  公开（公告）日：2003-03-26
• [EN] PHARMACEUTICAL DISINFECTANTS COMPRISING USNIC AND ESSENTIAL OILS<br/>[FR] DESINFECTANTS PHARMACEUTIQUES CONTENANT DE L'ACIDE USNIQUE ET DES HUILES ESSENTIELLES
  申请人：AD ZDRAVLJE FARMACEUTSKO HEMIJ

  公开号：WO2001095900A1

  公开（公告）日：2001-12-20

  The process relates to the pharmaceutical disinfective preparation on the basis of usnic acid sodium salt and medical plants (sage Salvia officinalis L., or fennel Foeniculum vulgare L., or thyme Thymus Vulgaris L., or peppermint Mentha piperita L.) or menthol, which is used as a common disinfective agent for external use in treatment of inflammation of the upper respiratory tract and oral cavity, caused by the action of pathogenic microorganisms. The invention presents the procedures for obtaining of the preparations in the form of: chewable tablets, tablets, gel, aerosol, as a base for deodorants, aromatic-antiseptic liquid for disinfection, in the form of wet napkin for intimate care, baby powder and other forms for mentioned purpose.
• [EN] COMPOSITION OF NATURAL EXTRACTS HAVING ANTIBACTERIAL OR BACTERIOSTATIC ACTIVITY ALSO FOR GRAM-NEGATIVE BACTERIA<br/>[FR] COMPOSITION D'EXTRAITS NATURELS AYANT UNE ACTIVITÉ ANTIBACTÉRIENNE OU BACTÉRIOSTATIQUE ÉGALEMENT POUR DES BACTÉRIES À GRAM NÉGATIF
  申请人：VESTATIS GMBH

  公开号：WO2021100026A1

  公开（公告）日：2021-05-27

  The present invention relates to a mixture M of natural origin comprising an usnic acid and/or a salt thereof, preferably an usnic acid sodium salt, in the racemic or dextrorotatory D(+) form. Furthermore, the present invention relates to an inclusion compound (ci) comprising or, alternatively consisting of: (i) a D-usnic acid as an enantiomer, or a salt thereof, or mixtures thereof, of natural origin, and (ii) beta-cyclodextrins. The present invention also relates to the use of said mixture M and/or said inclusion compound (ci) as antibacterial, antibacterial proliferative, bacteriostatic, microbicidal, anti-mould, anti-yeast, antifungal or antimycotic agent, preferably against Gram-positive and/or Gram-negative bacteria. Furthermore, the present invention relates to a method for rendering a surface antibacterial, antibacterial proliferative, bacteriostatic, microbicidal, anti-mould, anti-yeast, antifungal or antimycotic, preferably against Gram-positive and/or Gram-negative bacteria, said method provides for the application - by means of spray, roller or brush technique - of said mixture M and/or said inclusion compound (ci) on said surface.
• [EN] IMPROVED FILTERING MASK<br/>[FR] MASQUE FILTRANT AMÉLIORÉ
  申请人：U EARTH BIOTECH LTD

  公开号：WO2021186347A1

  公开（公告）日：2021-09-23

  The present invention relates to personal protective equipment, specifically to a filtering device for the protection of the respiratory tract, which can be worn on the face of a user. In particular, the present invention relates to a wearable filtering mask comprising said filtering device (filtering means) for the protection of the respiratory tract and, furthermore, it relates to said filtering device (filtering means), preferably in the form of multilayer filtering means. Lastly, the present invention relates to a face mask that can be worn and configured to filter air.