1-(6-hydroxyhexyl)-3-methylimidazolium bromide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(6-hydroxyhexyl)-3-methylimidazolium bromide
• 英文别名: 1-(6-Hydroxyhexyl)-3-methylimidazolium bromide；6-(3-methylimidazol-3-ium-1-yl)hexan-1-ol;bromide
• 化学式: Br*C₁₀H₁₉N₂O
• 分子量: 263.178
• InChiKey: KWDSVKVUTLXHND-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.13
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  29
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(6-hydroxyhexyl)-3-methylimidazolium bromide 、 甲基丙烯酰氯 在 2,6-二叔丁基-4-甲基苯酚 作用下， 以 乙腈 为溶剂， 反应 48.0h， 以97%的产率得到1-[(6-methacryloyloxy)hexyl]-3-methylimidazolium bromide
  参考文献：
  名称：

  New Method for Synthesis of Methacrylate-Type Polymerizable Ionic Liquids

  摘要：

  A new method for the synthesis of polymerizable ionic liquids bearing a methacrylate moiety was developed with the aim to avoid premature polymerization of synthesized compounds. Spacer length between the imidazolium cation and the polymerizable functional group varied from 2 to 10 carbon atoms. Different 1-(n-hydroxyalkyl)-3-methylimidazolium bromides and 1-[n-(methacryloyloxy)-alkyl]-3-methylimidazolium bromides were obtained with very good yields (more than 90%). [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource: Full experimental and spectral details.]

  DOI：

  10.1080/00397911.2012.745159
• 作为产物：
  描述：

  1,6-己二醇 在 氢溴酸 作用下， 以 水 、 甲苯 为溶剂， 反应 48.0h， 生成 1-(6-hydroxyhexyl)-3-methylimidazolium bromide
  参考文献：
  名称：

  New Method for Synthesis of Methacrylate-Type Polymerizable Ionic Liquids

  摘要：

  A new method for the synthesis of polymerizable ionic liquids bearing a methacrylate moiety was developed with the aim to avoid premature polymerization of synthesized compounds. Spacer length between the imidazolium cation and the polymerizable functional group varied from 2 to 10 carbon atoms. Different 1-(n-hydroxyalkyl)-3-methylimidazolium bromides and 1-[n-(methacryloyloxy)-alkyl]-3-methylimidazolium bromides were obtained with very good yields (more than 90%). [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource: Full experimental and spectral details.]

  DOI：

  10.1080/00397911.2012.745159

文献信息

• PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID
  申请人：Zhang Suojiang

  公开号：US20130072727A1

  公开（公告）日：2013-03-21

  Disclosed is a process for producing ethylene glycol catalyzed by an ionic liquid, characterized in that the process includes the following three steps: (a) a carbonylation step of ethylene oxide and CO 2 catalyzed by an ionic liquid composite catalyst comprising a hydroxyl functionalized ionic liquid and an alkali metal salt under an aqueous condition to produce ethylene carbonate and ethylene glycol; (b) a hydrolysis step of reacting the reaction solution containing ethylene carbonate and the ionic liquid composite catalyst obtained in step (a) with water to produce ethylene glycol; (c) a purification step of dehydrating and refining ethylene glycol from the aqueous solution containing ethylene glycol and the catalyst produced in step (b). The present process has the following advantages: the catalyst has high activity, high suitability, and good stability, the reaction condition is wild, the conversion of ethylene oxide is high, the selectivity of ethylene glycol is high, and the process is simple.

  揭示了一种由离子液体催化生产乙二醇的过程，其特征在于该过程包括以下三个步骤：(a) 由含有羟基官能化离子液体和碱金属盐的离子液体复合催化剂在水相条件下催化乙烯氧化物和CO2的羰基化步骤，以产生碳酸乙烯酯和乙二醇；(b) 将步骤(a)中获得的含有碳酸乙烯和离子液体复合催化剂的反应溶液与水反应以产生乙二醇的水解步骤；(c) 从含有乙二醇和步骤(b)中产生的催化剂的水溶液中脱水和精制乙二醇的纯化步骤。该过程具有以下优点：催化剂活性高、适用性强、稳定性好，反应条件宽松，乙烯氧化物转化率高，乙二醇选择性高，过程简单。
• Preparation of Functionalized Imidazolium Salts under Microwave Irradiation
  作者：Shih‐Kang Fu、Shiuh‐Tzung Liu

  DOI：10.1080/00397910600634464

  日期：2006.6

  Abstract A direct alkylation of a substituted imidazole to prepare the corresponding functionalized ionic liquid has been developed in excellent yields under microwave irradiation.

  摘要 取代咪唑直接烷基化制备相应的功能化离子液体已在微波辐射下以优异的产率得到开发。
• System and method for movement and timing control
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US10207269B2

  公开（公告）日：2019-02-19

  The present invention relates to fluidic systems for controlling one or more fluids and/or one or more reagents. These systems can be used in combination with one or more devices for assaying, processing, and/or storing samples. In particular, the systems and related methods can allow for dispensing fluid in a controlled manner and/or introducing pause(s) when implementing assays or processes.

  本发明涉及用于控制一种或多种流体和/或一种或多种试剂的流体系统。这些系统可与一个或多个用于化验、处理和/或储存样品的装置结合使用。特别是，这些系统和相关方法可以在实施化验或流程时以受控方式分配流体和/或引入暂停。
• FLUIDIC DEVICES AND SYSTEMS FOR SAMPLE PREPARATION OR AUTONOMOUS ANALYSIS
  申请人：TALIS BIOMEDICAL CORPORATION

  公开号：EP2839260B1

  公开（公告）日：2018-07-18
• FLUIDIC DEVICES FOR BIOSPECIMEN PRESERVATION
  申请人：UNIVERSITY OF CHICAGO

  公开号：US20130280725A1

  公开（公告）日：2013-10-24

  The present invention relates to fluidic devices for preparing, processing, storing, preserving, and/or analyzing samples. In particular, the devices and related systems and methods allow for preservation or storage of samples (e.g., biospecimen samples) by using one or more of a bridge, a membrane, and/or a desiccant.