N-Br-Valine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-Br-Valine
• 英文别名: (2S)-2-(bromoamino)-3-methylbutanoic acid
• 化学式: C₅H₁₀BrNO₂
• 分子量: 196.044
• InChiKey: KPUVTFZXERZCKQ-BYPYZUCNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-Br-Valine 以 水 为溶剂， 生成 2-氧代-3-甲基丁酸 、 二氧化碳 、 异丁醛
  参考文献：
  名称：

  General base catalysis in the decomposition ofN-Cl-Valine in aqueous solution

  摘要：

  AbstractThis article analyzes the kinetics of the decomposition of N‐Cl‐Valine in aqueous solution, which is formed rapidly by chlorination of Valine with sodium hypochlorite. A general‐base catalyzed process not yet described is reported. The experimental evidence shows two competitive decomposition paths: an unimolecular concerted fragmentation process (k = (1.8 ± 0.1) · 10−4 s−1 at 298 K) and the other one is an E2 elimination process whose importance increases with pH and depends on the nature and the concentration of the bases present in the medium. © 1994 John Wiley & Sons, Inc.

  DOI：

  10.1002/kin.550261008
• 作为产物：
  描述：

  L-缬氨酸 在 次溴酸 作用下， 生成 N-Br-Valine
  参考文献：
  名称：

  General base catalysis in the decomposition ofN-Cl-Valine in aqueous solution

  摘要：

  AbstractThis article analyzes the kinetics of the decomposition of N‐Cl‐Valine in aqueous solution, which is formed rapidly by chlorination of Valine with sodium hypochlorite. A general‐base catalyzed process not yet described is reported. The experimental evidence shows two competitive decomposition paths: an unimolecular concerted fragmentation process (k = (1.8 ± 0.1) · 10−4 s−1 at 298 K) and the other one is an E2 elimination process whose importance increases with pH and depends on the nature and the concentration of the bases present in the medium. © 1994 John Wiley & Sons, Inc.

  DOI：

  10.1002/kin.550261008

文献信息

• General base catalysis in the decomposition of<i>N</i>-Cl-Valine in aqueous solution
  作者：Ll Abia、X. L. Armesto、M. Canle L.、M. V. García、M. Losada、J. A. Santaballa

  DOI：10.1002/kin.550261008

  日期：1994.10

  AbstractThis article analyzes the kinetics of the decomposition of N‐Cl‐Valine in aqueous solution, which is formed rapidly by chlorination of Valine with sodium hypochlorite. A general‐base catalyzed process not yet described is reported. The experimental evidence shows two competitive decomposition paths: an unimolecular concerted fragmentation process (k = (1.8 ± 0.1) · 10−4 s−1 at 298 K) and the other one is an E2 elimination process whose importance increases with pH and depends on the nature and the concentration of the bases present in the medium. © 1994 John Wiley & Sons, Inc.