2-bromoethyl 2-phenylpropanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-bromoethyl 2-phenylpropanoate
• 英文别名: 2-Bromoethyl 2-phenylpropanoate
• 化学式: C₁₁H₁₃BrO₂
• 分子量: 257.127
• InChiKey: TVJFUKLDBJESJW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  α-Bromopropiophenone cyclic ethylene acetal 在 basolite C300 作用下， 以 苯 为溶剂， 反应 6.0h， 生成 2-bromoethyl 2-phenylpropanoate 、 2-溴苯丙酮
  参考文献：
  名称：

  探究金属-有机骨架[Cu3（btc）2]（BTC =苯-1,3,5-三羧酸盐）的路易斯酸度和催化活性。

  摘要：

  设计了一种优化程序，用于制备微孔金属有机骨架（MOF）[Cu3（btc）2]（BTC =苯-1,3,5-三羧酸酯）。通过X射线衍射，光学显微镜，SEM，X射线光电子能谱，N2吸附，热重分析和红外光谱对吸附的CO进行表征。CO吸附在少量Cu2O杂质上，尤其是在游离CuII上框架中的协调站点。[Cu3（btc）2]是用于萜烯衍生物异构化的高选择性路易斯酸催化剂，例如将α-pine烯氧化物重排为樟脑醛和将香茅醛环化为异胡薄荷醇。通过使用2-溴苯乙酮的乙烯缩酮作为测试底物，证明了[Cu3（btc）2]中的活性位是硬路易斯酸。催化剂稳定性，

  DOI：

  10.1002/chem.200600220

文献信息

• CC bond formation strategy through ecocatalysis: Insights from structural studies and synthetic potential
  作者：Claire Garel、Brice-Loïc Renard、Vincent Escande、Anouk Galtayries、Peter Hesemann、Claude Grison

  DOI：10.1016/j.apcata.2015.01.021

  日期：2015.9

  We report the elaboration of novel bio-sourced ecocatalysts for Heck and Suzuki cross-coupling reactions. Ecocatalysis is based on the recycling of metals issued from phytoremediation or rehabilitation, and an innovative chemical valorization of the subsequent biomass in the field of catalysis. Here, we describe the efficient palladium accumulation by plants (Brassica juncea, Lolium multiflorum) via rhizofiltration. Taking advantage of the remarkable ability of the selected plants to accumulate Pd(II) species into their roots, these latter can be directly used for the preparation of ecocatalysts, called Eco-Pd (R). The formed Eco-Pd (R) catalysts are thoroughly characterized via ICP-MS, XRD, XPS, TEM, SEM in order to elucidate the chemical composition and morphology of the formed materials. Significant differences to conventional Pd-based catalysts such as palladium(II) chloride can principally be related to a particular Lewis acid behavior of the Eco-Pd (R) catalysts. Finally, the obtained Eco-Pd (R) appear as highly active catalysts in Heck and Suzuki cross-coupling reactions necessitating considerably lower Pd quantity compared to precedently reported bio-sourced palladium containing catalysts. (C) 2015 Elsevier B.V. All rights reserved.