((2-环戊基苯氧基)甲基)-环氧乙烷 | 28163-40-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: ((2-环戊基苯氧基)甲基)-环氧乙烷
• 中文别名: N-叔-丁基-N-(2,3-环氧丙基)苯甲基胺
• 英文名称: ((2-Cyclopentylphenoxy)methyl)oxirane
• 英文别名: 2-[(2-cyclopentylphenoxy)methyl]oxirane
• CAS: 28163-40-8
• 化学式: C₁₄H₁₈O₂
• 分子量: 218.296
• InChiKey: NGWPLKBZYFYPHG-UHFFFAOYSA-N

物化性质

• 溶解度：
  可溶于二氯甲烷；甲醇

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  21.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  ((2-环戊基苯氧基)甲基)-环氧乙烷 、 叔丁胺 生成 喷布特罗
  参考文献：
  名称：

  Haertfelder; Lessenich; Schmitt, Arzneimittel-Forschung/Drug Research, 1972, vol. 22, # 5, p. 930 - 932

  摘要：

  DOI：
• 作为产物：
  描述：

  2-环戊基苯酚 、 环氧氯丙烷 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 生成 ((2-环戊基苯氧基)甲基)-环氧乙烷
  参考文献：
  名称：

  Design and synthesis of new potent, silent 5-HT1A antagonists by covalent coupling of aminopropanol derivatives with selective serotonin reuptake inhibitors

  摘要：

  Hybrid molecules built up by covalent coupling of aminopropanol derivatives (especially pindolol) with antidepressant drugs like fluoxetine, paroxetine or milnacipran were found to be potent and silent 5-HT1A antagonists (K-B < 1 nM for 7c and 9a). (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(98)00619-2

文献信息

• Use of 5-HT1A receptor agonist compounds for inhibiting gastric acid secretion
  申请人：ELI LILLY AND COMPANY

  公开号：EP0455510B1

  公开（公告）日：1996-11-27
• PROCESS FOR PRODUCING GLYCIDE DERIVATIVE
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP0603404B1

  公开（公告）日：1999-03-17
• Stabilizer or Binder and Manufacturing Method Thereof for Phosphorescent Materials
  申请人：Wah Hong Industrial Corp.

  公开号：US20160194557A1

  公开（公告）日：2016-07-07

  A manufacturing method of phosphor stabilizer includes: modifying trimethoxysilylpropyl with polyethylenimine in methylbenzene to obtain a first solution; heating the first solution at a predetermined temperature; dissolving epoxide in methylbenzene to obtain a second solution; and reacting the first solution with the second solution by stirring to obtain a reactant. The reactant is a stabilizer or a binder to combine with a phosphor or a quantum dot material to form a synthetic which is further cooled and purified to obtain a colloid material. The synthetic has a functional group to combine with the phosphor or the quantum dot material for enhancing dispersion, thermal stability and light absorbability for light emitting.
• US4863949A
  申请人：——

  公开号：US4863949A

  公开（公告）日：1989-09-05
• US5096908A
  申请人：——

  公开号：US5096908A

  公开（公告）日：1992-03-17