(2R,3S,4S,5S,6R)-2-(羟基甲基)-6-[(2R,3S,4R,5S,6S)-4,5,6-三羟基-2-(羟基甲基)四氢吡喃-3-基]氧基四氢吡喃-3,4,5-三醇 | 149116-55-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: (2R,3S,4S,5S,6R)-2-(羟基甲基)-6-[(2R,3S,4R,5S,6S)-4,5,6-三羟基-2-(羟基甲基)四氢吡喃-3-基]氧基四氢吡喃-3,4,5-三醇
• 中文别名: 4-O-吡喃鼠李糖基-(1-6)-甘露吡喃烷
• 英文名称: β-1,4-mannobiose
• 英文别名: mannobiose；α-Man-(1→4)-α-Man；4-O-(β-D-Mannopyranosyl)-D-mannose；(2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
• CAS: 149116-55-2
• 化学式: C₁₂H₂₂O₁₁
• 分子量: 342.3
• InChiKey: GUBGYTABKSRVRQ-XABDMIIQSA-N

物化性质

• 沸点：
  667.9±55.0 °C(Predicted)
• 密度：
  1.76±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -4.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  190
• 氢给体数：
  8
• 氢受体数：
  11

文献信息

• IMMUNOGENIC NANOMEDICINE COMPOSITION AND PREPARATION AND USES THEREOF
  申请人：Genetic Immunity Kft

  公开号：EP2453911A1

  公开（公告）日：2012-05-23
• [EN] IMMUNOGENIC NANOMEDICINE COMPOSITION AND PREPARATION AND USES THEREOF<br/>[FR] COMPOSITION DE NANOMÉDICAMENT IMMUNOGÈNE, PRÉPARATION ET UTILISATIONS DE CETTE COMPOSITION
  申请人：GENETIC IMMUNITY KFT

  公开号：WO2010125544A1

  公开（公告）日：2010-11-04

  The invention belongs to the field of immunotherapy and vaccines. More particularly, the invention relates to a pharmaceutical composition comprising nanoparticles being composed of macromolecules and linear polyethyleneimine (1-PEI) or 1-PEI derivative in a pharmaceutically acceptable liquid formulation, as well as a method for the preparation thereof. Uses of said compositions are also provided.