(4-乙氧基苯基)膦酸 | 69387-02-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: (4-乙氧基苯基)膦酸
• 英文名称: 4-ethoxyphenylphosphonic acid
• 英文别名: (4-ethoxy-phenyl)-phosphonic acid；(4-Aethoxy-phenyl)-phosphonsaeure；1-Aethoxy-benzol-phosphinsaeure-(4)；4-Aethoxy-phenylphosphinsaeure；Phenetol-phosphinsaeure-(4)；(4-ethoxyphenyl)phosphonic acid
• CAS: 69387-02-6
• 化学式: C₈H₁₁O₄P
• mdl: MFCD00019973
• 分子量: 202.147
• InChiKey: ORUZLAKPEKBACC-UHFFFAOYSA-N

物化性质

• 沸点：
  391.6±44.0 °C(Predicted)
• 密度：
  1.34±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (4-乙氧基苯基)膦酸 在 sodium hydroxide 、 双(2-氧代-3-恶唑烷基)次磷酰氯 、 三乙胺 作用下， 以 乙腈 为溶剂， 反应 116.0h， 生成
  参考文献：
  名称：

  Differential binding energy: a detailed evaluation of the influence of hydrogen-bonding and hydrophobic groups on the inhibition of thermolysin by phosphorus-containing inhibitors

  摘要：

  Two series of phosphorus-containing peptide analogues, 3 (Cbz-Gly-psi(PO2-CH2)Leu-Xaa) and 4 (Cbz-Gly-psi-(PO2-NH)Leu-psi[CO2]Xaa), have been synthesized and evaluated as inhibitors of the zinc endopeptidase thermolysin. In comparison with the previously reported phosphonamidates 1, the phosphinates 3 lose only 0.1 kcal/mol in binding affinity, whereas the depsipeptides 4 are bound 2.7 kcal/mol more weakly; these values are contrasted to the 4.0 kcal/mol reduction in binding affinity observed for the phosphonates 2 (Cbz-Gly-psi(PO2-O)Leu-Xaa) in comparison to 1 (Cbz-Gly-psi(PO2-NH)Leu-Xaa). The observed effects are interpreted through consideration of the differences in active-site and solvent interactions. For the comparison between the diamides 1 and the depsipeptides 4, a full accounting of the balance between these interactions can be approached. The arylphosphonates 5 (Aryl-psi(PO2-O)Leu-Leu) were synthesized and evaluated to investigate the importance of phosphonate basicity on the overall binding affinity of these zinc-coordinating inhibitors; the inhibitor K(i) values were found to be independent of phosphonate p(K)a, indicating that the basicity of the phosphonate moiety exerts counterbalancing effects on the energies of zinc coordination and solvation. For analysis of the influence of structural variations on observed affinity, the definition of "differential binding energy" is introduced as a practical alternative to the concept of "intrinsic binding energy".

  DOI：

  10.1021/ja00001a043
• 作为产物：
  描述：

  苯乙醚 在 三氯化铝 、 氯 、 三氯化磷 作用下， 生成 (4-乙氧基苯基)膦酸
  参考文献：
  名称：

  Michaelis, Justus Liebigs Annalen der Chemie, 1896, vol. 293, p. 265

  摘要：

  DOI：

文献信息

• Verfahren zur Herstellung und Stabilisierung von aliphatischen Sechsringcarbonaten
  申请人：BAYER AG

  公开号：EP0816354A1

  公开（公告）日：1998-01-07

  Die Erfindung betrifft ein Verfahren zur Herstellung von Sechsringcarbonaten der Formel durch Umesterung von 1,3-Propandiol-Verbindungen mit Kohlensäureestern und anschließende destillative Depolymerisation des zunächst entstehenden Oligo- bzw. Polycarbonats, worin man sowohl für die Umesterung als auch für die Depolymerisation einen oder mehrere Katalysatoren aus der Gruppe der Verbindungen von Sn, Ti oder Zr einsetzt und gegebenenfalls den Destillationsrückstand mindestens teilweise in die Umesterung zurückführt. Solche Sechsringcarbonate können weiterhin durch Zusatz Kleiner Mengen von Säuren des Schwefels oder Phosphors oder deren Estern oder Salzen gegen unerwünschte Polymerisation stabilisiert werden.

  本发明涉及一种通过 1,3-丙二醇化合物与碳酸酯的酯交换反应，以及随后对最初 形成的低碳酸酯或聚碳酸酯进行蒸馏解聚，生产式 6-环碳酸盐的工艺。 通过 1,3-丙二醇化合物与碳酸酯的酯交换反应，以及随后对最初形成的低聚或聚碳酸酯进行蒸馏解聚，其中一种或多种 Sn、Ti 或 Zr 化合物催化剂同时用于酯交换反应和解聚反应，如果合适，蒸馏残余物至少部分循环用于酯交换反应。还可以通过添加少量硫酸或磷酸或其酯类或盐类来稳定这种六环碳酸酯，防止发生不希望的聚合反应。
• PHOSPHORUS ELECTROLYTIC SOLUTION CONTAINING MAGNESIUM IONS
  申请人：FUJIFILM Wako Pure Chemical Corporation

  公开号：EP3467931A1

  公开（公告）日：2019-04-10

  The present invention relates to an electrolytic solution for a magnesium battery, formed by mixing a compound represented by the following general formula (I), a Lewis acid or a compound represented by the following general formula (A), and a solvent; and the like. In the formula, m represents 0 or 2, n represents 2 in a case of m=0 and represents 0 or 1 in a case of m=2, X1 represents a chlorine atom or a bromine atom, and two R1's each independently represent a magnesium chloride oxy group; a magnesium bromide oxy group; an alkyl group which may have a halogeno group or the like as a substituent; an alkoxy group; an aryl group which may have an alkoxy group or the like as a substituent; an aryloxy group which may have an alkoxy group or the like as a substituent; or a group represented by the following general formula (1), and two R1's may also form the following general formula (2).}         Mg [N(SO2R10)2]2     (A) (In the formula, four R10's each independently represent an alkyl group, a perfluoroalkyl group, a phenyl group, or a perfluorophenyl group.)

  本发明涉及一种用于镁电池的电解溶液，该溶液由以下通式（I）代表的化合物、路易斯酸或以下通式（A）代表的化合物和溶剂等混合而成。 在式中，m 代表 0 或 2，n 在 m=0 的情况下代表 2，在 m=2 的情况下代表 0 或 1，X1 代表氯原子或溴原子，两个 R1 各自独立地代表氯化镁氧基；溴化镁氧基；烷基，其取代基可以是卤代基或类似物；烷氧基；可具有烷氧基或类似基团作为取代基的芳基；可具有烷氧基或类似基团作为取代基的芳氧基；或由以下通式(1)表示的基团，两个 R1 还可组成以下通式(2)。} 镁[N(SO2R10)2]2 (A) (式中，四个 R10 各自独立地代表一个烷基、一个全氟烷基、一个苯基或一个全氟苯基）。
• Process for preparing a crystalline organic semiconductor material
  申请人：BASF SE

  公开号：US10224485B2

  公开（公告）日：2019-03-05

  Provided are a process for preparing a crystalline organic semiconductor material wherein the conditions of crystallization lead to the formation of crystals at the gas liquid interface having advantageous semiconductor properties, the obtained crystalline organic semiconductor material and the use thereof for the production of organic semiconductor devices, in particular organic field effect transistors and organic solar cells.

  本发明提供了一种制备结晶有机半导体材料的工艺，在该工艺中，结晶条件导致在气液界面上形成具有良好半导体特性的晶体，所获得的结晶有机半导体材料及其用于生产有机半导体器件，特别是有机场效应晶体管和有机太阳能电池。
• Acrylic pressure-sensitive adhesive composition, acrylic pressure-sensitive adhesive layer, pressure-sensitive adhesive layer-attached substrate film, laminate, and image display device
  申请人：NITTO DENKO CORPORATION

  公开号：US10253220B2

  公开（公告）日：2019-04-09

  Provided are an acrylic pressure-sensitive adhesive composition including a (meth)acryl-based polymer and a phosphonic acid compound of formula (1): wherein R is a hydrogen atom or a hydrocarbon residue having 1 to 18 carbon atoms which may have an oxygen atom, or a salt thereof, the composition containing 0.005 to 3 parts by weight of the phosphonic acid compound of formula (1) based on 100 parts by weight of the (meth)acryl-based polymer; a pressure-sensitive adhesive layer made from the acrylic pressure-sensitive adhesive composition; a pressure-sensitive adhesive layer-attached substrate film having the pressure-sensitive adhesive layer; a laminate including the pressure-sensitive adhesive layer-attached substrate film; and an image display device including the laminate or the pressure-sensitive adhesive layer-attached substrate film.

  本发明提供了一种丙烯酸压敏胶组合物，其中包括一种（甲基）丙烯酸基聚合物和一种式（1）的膦酸化合物： 其中 R 是氢原子或具有 1 至 18 个碳原子且可能具有一个氧原子的烃残基，或其盐，该组合物含有 0.005至3份重量的式(1)膦酸化合物（以100份重量的(甲基)丙烯基聚合物为基准）；由丙烯酸压敏粘合剂组合物制成的压敏粘合层；具有该压敏粘合层的压敏粘合层附着基底膜；包括该压敏粘合层附着基底膜的层压板；以及包括该层压板或该压敏粘合层附着基底膜的图像显示装置。
• Organic semiconductor composition comprising a liquid medium
  申请人：BASF SE

  公开号：US10454037B2

  公开（公告）日：2019-10-22

  Disclosed are a novel semiconductor composition comprising at least one organic semiconductor in a liquid medium and the use thereof the production of organic semiconductor devices, in particular organic field effect transistors, organic solar cells, light-emitting diodes and sensors.

  本发明公开了一种新型半导体组合物，该组合物由液体介质中的至少一种有机半导体组成，并利用该组合物生产有机半导体器件，特别是有机场效应晶体管、有机太阳能电池、发光二极管和传感器。