(4-异丙基-1,4-环己二烯-1-基)甲醇 | 22539-72-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: (4-异丙基-1,4-环己二烯-1-基)甲醇
• 英文名称: p-mentha-1,4-dien-7-ol
• 英文别名: p-menth-1,4-dien-7-ol；(4-propan-2-ylcyclohexa-1,4-dien-1-yl)methanol
• CAS: 22539-72-6
• 化学式: C₁₀H₁₆O
• 分子量: 152.236
• InChiKey: IRZQJXCCKXGQFV-UHFFFAOYSA-N

物化性质

• 沸点：
  70 °C(Press: 0.3 Torr)
• 密度：
  0.953±0.06 g/cm3(Predicted)
• LogP：
  2.754 (est)
• 保留指数：
  1329.5;1333;1332;1315;1315

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2906199090

文献信息

• [EN] PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES AND METHODS OF USE<br/>[FR] COMPOSITIONS PHARMACEUTIQUES COMPRENANT DES DÉRIVÉS DE POH ET PROCÉDÉS D'UTILISATION
  申请人：NEONC TECH INC

  公开号：WO2018195149A1

  公开（公告）日：2018-10-25

  The present invention provides for a method of treating a disease such as cancer, comprising the step of administering to a patient a therapeutically effective amount of a perillyl alcohol derivative such as a perillyl alcohol ester, or an isoperillyl alcohol derivative such as an isoperillyl alcohol ester. The derivative may be a perillyl alcohol or an isoperillyl alcohol conjugated with a therapeutic agent such as valproic acid. The route of administration may vary, including inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.

  本发明提供了一种治疗疾病（如癌症）的方法，包括向患者施用治疗有效量的某种柠檬醇衍生物，例如柠檬醇酯或异柠檬醇衍生物，如异柠檬醇酯。该衍生物可以是与治疗剂（如丙戊酸）结合的柠檬醇或异柠檬醇。给药途径可以有所不同，包括吸入、鼻内、口服、经皮、静脉内、皮下或肌肉内注射。
• Pyrrole compound, method of making same, and aroma composition, food, drink and cosmetics containing same
  申请人：T. HASEGAWA CO., LTD.

  公开号：US11332694B2

  公开（公告）日：2022-05-17

  A compound represented by the following formula (1): wherein, R1 is a linear or branched alkyl group having 1 to 3 carbon atoms or a hydroxyl group; and R2 is a 1-pyrrolyl group, a 2-pyrrolyl group, or a 3-pyrrolyl group. The present invention can provide a means highly effective in contributing to savory roasting flavor and capable of imparting fragrance with natural feeling.

  下式(1)所代表的化合物： 其中，R1 是具有 1 至 3 个碳原子的直链或支链烷基或羟基；R2 是 1-吡咯基、2-吡咯基或 3-吡咯基。本发明可以提供一种方法，它能高效地促进咸味烘焙风味，并能赋予香味自然的感觉。
• PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES AND METHODS OF USE
  申请人：Neonc Technologies, Inc.

  公开号：EP3612185A1

  公开（公告）日：2020-02-26
• PYRROLE COMPOUND, AROMA COMPOSITION, AND FOOD AND DRINK AND COSMETICS CONTAINING THE SAME
  申请人：T. HASEGAWA CO., LTD.

  公开号：US20200157463A1

  公开（公告）日：2020-05-21

  A compound represented by the following formula (1): wherein, R 1 is a linear or branched alkyl group having 1 to 3 carbon atoms or a hydroxyl group; and R 2 is a 1-pyrrolyl group, a 2-pyrrolyl group, or a 3-pyrrolyl group. The present invention can provide a means highly effective in contributing to savory roasting flavor and capable of imparting fragrance with natural feeling.

表征谱图