(4R)-7-[(1S)-4-羟基-1,4-二甲基环己-2-烯-1-基]-7-甲基-1-氧杂螺[2.4]庚烷-4,5-二醇 | 109890-37-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: (4R)-7-[(1S)-4-羟基-1,4-二甲基环己-2-烯-1-基]-7-甲基-1-氧杂螺[2.4]庚烷-4,5-二醇
• 英文名称: (7R)-4-[(1S)-4-hydroxy-1,4-dimethylcyclohex-2-en-1-yl]-4-methyl-1-oxaspiro[2.4]heptane-6,7-diol
• CAS: 109890-37-1
• 化学式: C₁₅H₂₄O₄
• 分子量: 268.35
• InChiKey: FPANWDWGPATUTH-ULMRJCCDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  73.2
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Trichothecene-transforming alcohol dehydrogenase, method for transforming trichothecenes and trichothecene-transforming additive
  申请人：Erber Aktiengesellschaft

  公开号：US11001812B2

  公开（公告）日：2021-05-11

  An alcohol dehydrogenase of sequence ID numbers 2, 3 or 4 containing metal ions and a quinone cofactor, or in addition, a functional variant exhibiting a sequence identity of at least 80%, preferably at least 86%, especially preferred at least 89% and at least one redox cofactor for the transformation of at least one trichothecene exhibiting a hydroxyl group on the C-3 atom, as well as a method for the enzymatic transformation of trichothecenes and a trichothecene-transforming additive.

  一种序列 ID 号为 2、3 或 4 的醇脱氢酶，含有金属离子和醌辅助因子，或此外还含有一种功能变体，其序列同一性至少为 80%，优选至少为 86%，特别优选至少为 89%，并含有至少一种氧化还原辅助因子，用于转化至少一种 C-3 原子上带有羟基的单端孢霉烯，以及一种单端孢霉烯酶促转化方法和一种单端孢霉烯转化添加剂。
• TRICHOTHECENE-TRANSFORMING ALCOHOL DEHYDROGENASE, METHOD FOR TRANSFORMING TRICHOTHECENES AND TRICHOTHECENE-TRANSFORMING ADDITIVE
  申请人：Erber Aktiengesellschaft

  公开号：US20180080011A1

  公开（公告）日：2018-03-22

  A alcohol dehydrogenase of sequence ID no. 1 containing metal ions and a quinone cofactor, or in addition, a functional variant exhibiting a sequence identity of at least 80%, preferably at least 86%, especially preferred at least 89% and at least one redox cofactor for the transformation of at least one trichothecene exhibiting a hydroxyl group on the C-3 atom, as well as a method for the enzymatic transformation of trichothecenes and a trichothecene-transforming additive.
• [EN] METHODS AND COMPOSITIONS FOR DEGRADING DEOXYNIVALENOL<br/>[FR] PROCÉDÉS ET COMPOSITIONS POUR LA DÉGRADATION DE DÉSOXYNIVALÉNOL
  申请人：[en]ERBER AKTIENGESELLSCHAFT

  公开号：WO2022084501A1

  公开（公告）日：2022-04-28

  The present invention relates to means and methods for degrading DON and/or DON derivative/s comprising a polypeptide comprising an amino acid sequence having at least 70% identity to the amino acid sequence set forth in SEQ ID NO: 1.