1-[4-(2-Hydroxyethoxy)-3-methoxyphenyl]ethanone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-[4-(2-Hydroxyethoxy)-3-methoxyphenyl]ethanone
• 化学式: C₁₁H₁₄O₄
• mdl: MFCD09936971
• 分子量: 210.23
• InChiKey: VPGKITVYIBYXEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Method of identifying compounds useful to treat neuronal degenerative diseases
  申请人：Engelhardt John F.

  公开号：US20080206792A1

  公开（公告）日：2008-08-28

  Methods of identifying agents that inhibit ROS by altering the binding of a GTPase such as Rac to SOD, agents identified by the method, and methods of using compounds that inhibit ROS to inhibit or treat neuronal degenerative diseases, are provided.
• Methods and compounds to alter virus infection
  申请人：Engelhardt John F.

  公开号：US20080261201A1

  公开（公告）日：2008-10-23

  The invention provides a method to identify an agent that alters parvovirus transduction of mammalian cells. Also provided is a method to enhance transgene expression in a mammalian cell, as well as a method to identify an agent that alters NADPH oxidase activity in parvovirus transduced mammalian cells.
• [EN] METHODS FOR CONTROLLING FREE RADICAL GENERATION BY INFLAMMATORY CELLS<br/>[FR] PROCEDES POUR LIMITER LA PRODUCTION DE RADICAUX LIBRES DUE A DES CELLULES INFLAMMATOIRES
  申请人：IDUN PHARMACEUTICALS

  公开号：WO1995022323A1

  公开（公告）日：1995-08-24

  (EN) Methods, compositions and compounds for the treatment of chronic inflammatory diseases, such as inflammatory bowel disease, are described. The methods, compositions and compounds of the invention are effective to inhibit the oxidative burst pathway.(FR) L'invention concerne des méthodes, des compositions et des composés pour le traitement de maladies inflammatoires chroniques telles que les infections intestinales inflammatoires. Les méthodes, compositions et composés selon l'invention sont efficaces pour inhiber la voie d'explosion oxydative.