6,6-dimethoxy-5,7-dihydro-4H-1,3-benzothiazol-2-amine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6,6-dimethoxy-5,7-dihydro-4H-1,3-benzothiazol-2-amine
• 化学式: C₉H₁₄N₂O₂S
• 分子量: 214.29
• InChiKey: CYEPKLQJKZBKJL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  85.6
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Process for preparation of 2-amino-6 (alkyl) amino-4,5,6,7-tetrahydrobenzothiazoles
  申请人：——

  公开号：US20040029936A1

  公开（公告）日：2004-02-12

  A new process to obtain pramipexole and related products is described. The process involves the reaction of new compounds of formula (6), wherein R is hydrogen or acyl group, R 3 and R 4 are either the same and each of them represents an alkoxy group of 1-4 carbons or they together form a C 2 -C 5 alkylenedioxy group or an oxo-group, with an alkylamine in the presence of a reducing agent or a hydrogen gas with hydrogenation catalyst. A process to obtain new compounds of formula (6) is also described.

  描述了一种获取普拉米贝克索和相关产品的新工艺。该工艺涉及新化合物的反应，其化学式为（6），其中R为氢或酰基，R3和R4可以相同，且分别代表1-4碳原子的烷氧基，或它们一起形成一个C2-C5烷二氧基基团或一个氧基团，与一种烷基胺在还原剂或氢气与加氢催化剂的存在下发生反应。还描述了一种获得新化合物的工艺，其化学式为（6）。
• Colorants and intermediates therefor having branched poly(oxyalkylene)moieties, and their manufacture
  申请人：MILLIKEN RESEARCH CORPORATION

  公开号：EP0529162A1

  公开（公告）日：1993-03-03

  Colorants and compositions useful as a fugitive or permanent colorant for a variety of substrates, or as intermediates for their manufacture, and having one or more improved properties of enhanced aqueous washability, compatibility with and non-extractibility from thermoplastic resins, or reactivity with resins having reactive functionality, said composition having the formula C(Z)₁₋₈ wherein:    C is the residue of a reactant having from 1-8 nucleophilic site residues to which the Z moieties are attached; said Z moieties containing at least about 60 weight percent of poly(oxyalkylene) which is comprised of (a) at least one glycidol residue segment of 2-6 glycidol residues attached to a nucleophilic site of C, wherein said poly(oxyalkylene) contains a total of from 2-20 glycidol residues, (b) and wherein said poly(oxyalkylene) further contains the residues of one or more other epoxide reactants of ethylene oxide (EO), propylene oxide (PO), or butylene oxide (BO), or mixtures thereof, wherein said poly(oxyalkylene) contains a total of from about 10 to about 600 of said EO, PO or BO residues, or mixtures thereof, at least about 75 mole percent of which are EO residues, (c) and with the provisions that the ratio of the total of - O-PO- and -O-BO- linkages of all glycidol residues to the total of all functional oxy linkages of said glycidol residues is less than one, and the molar ratio of EO residues to glycidol residues is from 4 to 75.

  着色剂和组合物，可用作各种基材的褪色剂或永久性着色剂，或用作其制造的中间体，并具有一种或多种改进特性，即增强的水洗性、与热塑性树脂的相容性和不萃取性，或与具有反应官能团的树脂的反应性，所述组合物具有式 C(Z)₁₋₈ 其中，C 是反应物的残余物，反应物具有 1-8 个亲核部位残余物，Z 分子与反应物相连；所述 Z 分子含有至少约 60% 的聚(氧亚烷基)，该聚(氧亚烷基)是一种具有反应官能团的树脂： C 是反应物的残留物，该反应物具有 1-8 个亲核位点残留物，Z 分子附着在该残留物上；所述 Z 分子含有至少约 60 重量百分比的聚氧亚烷基，该聚氧亚烷基由以下物质组成 (a) 至少一个由 2-6 个缩水甘油残基组成的缩水甘油残基段，该段连接到 C 的亲核位点，其中所述聚（氧烷基）总共包含 2-20 个缩水甘油残基、 (b) 其中所述聚（氧烷基）进一步含有环氧乙烷（EO）、环氧丙烷（PO）或环氧丁 烷（BO）的一种或多种其它环氧化物反应物或其混合物的残基，其中所述聚（氧烷 基）总共含有约 10 至约 600 个所述环氧乙烷、环氧丙烷或环氧丁烷残基或其混 合物，其中至少约 75 摩尔％为环氧乙烷残基、 (c) 并规定所有缩水甘油残基的-O-PO-和-O-BO-链节总数与所述缩水甘油残基的所有官能氧链节总数之比小于1，且环氧乙烷残基与缩水甘油残基的摩尔比为4至75。
• PROCESS FOR PREPARATION OF 2-AMINO-6-(ALKYL) AMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLES
  申请人：Synthon B.V.

  公开号：EP1318986A1

  公开（公告）日：2003-06-18
• US5290921A
  申请人：——

  公开号：US5290921A

  公开（公告）日：1994-03-01
• US5591833A
  申请人：——

  公开号：US5591833A

  公开（公告）日：1997-01-07