(2S,3R,4S,5R)-2-(1,4-dihydroxynaphthalen-2-yl)oxyoxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4S,5R)-2-(1,4-dihydroxynaphthalen-2-yl)oxyoxane-3,4,5-triol
• 化学式: C₁₅H₁₆O₇
• 分子量: 308.28
• InChiKey: ZNQASMCVJWJQTF-KAOXEZKKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  120
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• Antiproliferative Compositions Comprising Aryl Substituted Xylopyranoside Derivatives
  申请人：Ellervik Ulf

  公开号：US20080027023A1

  公开（公告）日：2008-01-31

  Novel xylose based glycoside compounds that have xylose linked O-, S- or C-glycosidically to an aglycone containing several aromatic rings, and compositions that comprise the novel xylose based glycosides and non-xylose-based anti-tumor agents, pharmaceuticals or dietary supplements. The compounds or compositions are administered to treat proliferative diseases, including various forms of cancer.

  本发明涉及一种新型木糖基糖苷化合物，其将木糖与一个含有多个芳香环的无糖基连接，其中连接方式为O-, S-或C-糖苷化。此外，还提供了包含这种新型木糖基糖苷化合物和非木糖基抗肿瘤药物、药品或膳食补充剂的组合物。这些化合物或组合物可用于治疗增殖性疾病，包括各种癌症。
• Novel compounds
  申请人：——

  公开号：US20030092637A1

  公开（公告）日：2003-05-15

  The present invention relates to combinations of xylose compounds with other pharmaceutically active compounds, to pharmaceutical compositions comprising said combinations, as well as to use of these combinations for the manufacture of a medicament for treatment of proliferative disorders. In another aspect, the present invention relates to novel xylose compounds, to pharmaceutical compositions comprising said compounds, and to use of these compounds for the manufacture of a medicament or the treatment of proliferative disorders.

  本发明涉及木糖化合物与其他药用活性化合物的组合物、包含所述组合物的药物组合物，以及使用这些组合物制造治疗增殖性疾病的药物。另一方面，本发明涉及新型木糖化合物、包含上述化合物的药物组合物，以及使用这些化合物制造药物或治疗增殖性疾病。