Fruf1P(b2-1a)Glc

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Fruf1P(b2-1a)Glc
• 英文别名: [(2S,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-2-yl]methyl dihydrogen phosphate
• 化学式: C₁₂H₂₃O₁₄P
• 分子量: 422.28
• InChiKey: KDWJSKVQQPOWRR-UGDNZRGBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.3
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  236
• 氢给体数：
  9
• 氢受体数：
  14

文献信息

• [EN] COMPOSITIONS COMPRISING A STRIGOLACTAME COMPOUND FOR ENHANCED PLANT GROWTH AND YIELD<br/>[FR] COMPOSITIONS COMPRENANT UN COMPOSÉ DE STRIGOLACTAME POUR LA CROISSANCE ET LE RENDEMENT ACCRUS DE PLANTES
  申请人：BAYER IP GMBH

  公开号：WO2013139949A1

  公开（公告）日：2013-09-26

  The present invention relates to strigolactame derivatives of formula (I) that are active oh plants and to compositions comprising said derivatives. The present invention also relates to the use of said derivatives or compositions for enhancing the plant growth, yield, vigor and/or mycchorization and to corresponding methods.

  本发明涉及公式(I)的赤霉素衍生物，这些衍生物对植物具有活性，并且涉及包含该类衍生物的组合物。本发明还涉及利用这些衍生物或组合物来增强植物的生长、产量、活力和/或菌根化作用，以及相应的方法。
• DELIVERY MOLECULES FOR THERAPEUTICS
  申请人：Marina Biotech, Inc.

  公开号：US20170216227A1

  公开（公告）日：2017-08-03

  Activity-generating delivery molecules comprising the structure R 3 —(C═O)-Xaa-NH—R 4 wherein Xaa is any D- or L-amino acid residue with a non-hydrogen, substituted or unsubstituted side chain, R 3 —(C═O)— and —NH—R 4 are independently a long chain group, each long chain group containing one or more carbon-carbon double bonds, and salts, compositions and methods of use thereof. The activity-generating delivery compounds and compositions are useful for generating activity of an active agent in a cell, tissue, or subject.

  活性产生传递分子包括结构R3—(C═O)-Xaa-NH—R4，其中Xaa是任何具有非氢、取代或未取代侧链的D-或L-氨基酸残基，R3—(C═O)—和—NH—R4分别是长链基团，每个长链基团含有一个或多个碳-碳双键，以及其盐、组合物和使用方法。这些活性产生传递化合物和组合物有用于在细胞、组织或主体中产生活性剂的活性。
• ACTIVITY GENERATING DELIVERY MOLECULES
  申请人：Fam Renata

  公开号：US20120277289A1

  公开（公告）日：2012-11-01

  Activity-generating delivery molecules comprising the structure R 3 —(C═O)-Xaa-NH—R 4 wherein Xaa is any D- or L-amino acid residue with a non-hydrogen, substituted or unsubstituted side chain, R 3 —(C═O)— and —NH—R 4 are independently a long chain group, each long chain group containing one or more carbon-carbon double bonds, and salts, compositions and methods of use thereof. The activity-generating delivery compounds and compositions are useful for generating activity of an active agent in a cell, tissue, or subject.

  含有结构R3—(C═O)-Xaa-NH—R4的活性产生递送分子，其中Xaa是任何具有非氢取代或未取代侧链的D-或L-氨基酸残基，R3—(C═O)—和—NH—R4分别是长链基团，每个长链基团含有一个或多个碳-碳双键，以及其盐类、组合物和使用方法。这些活性产生递送化合物和组合物有助于在细胞、组织或主体中产生活性剂的活性。
• POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF
  申请人：THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICE

  公开号：US20160009644A1

  公开（公告）日：2016-01-14

  Disclosed herein are bisarylmethylthioacetamides and bisarylmethylthioethylamines useful as inhibitors of monoamine transporters. The compounds are potent and/or selective inhibitors of dopamine (DA), serotonin (5-HT), and/or norepinephrine (NE) reuptake via their respective transporters, DAT, SERT and NET. Also disclosed are methods for eliciting a wake-promoting or cognitive or attention enhancing effect and for treating substance use disorders, attention deficit (hyperactivity) disorder, depressive disorders, bipolar disorder or other neuropsychiatric disorders sleep disorders or cognitive impairment using the compounds.

  本文揭示了双芳基甲硫基乙酰胺和双芳基甲硫基乙胺作为单胺转运体抑制剂的用途。这些化合物是通过它们各自的转运体DAT、SERT和NET对多巴胺（DA）、5-羟色胺（5-HT）和/或去甲肾上腺素（NE）的再摄取具有强效和/或选择性抑制作用。还揭示了利用这些化合物引发促醒、认知或注意力增强效应以及治疗物质使用障碍、注意缺陷（多动）障碍、抑郁障碍、双相障碍或其他神经精神障碍、睡眠障碍或认知障碍的方法。
• Detection of cell membrane protein
  申请人：Becton, Dickinson and Company

  公开号：EP0174106A2

  公开（公告）日：1986-03-12

  The invention comprises a method for detecting cell proteins of microorganisms, such as the principal outer membrane protein of Chlamydia trachomatis having a mean molecular weight of 39.5 daltons. The method includes the steps of adding a buffer salt solution to a specimen suspected of containing bacterial antigens, raising the pH of the buffered solution so produced, incubating the solution, adding a neutralizing buffer to the solution to lower the pH, and assaying the sample by conventional immunoassay techniques. Optionally the sample solution is heated prior to incubation and then cooled afterwards before adding the neutralizing buffer.

  本发明包括一种检测微生物细胞蛋白的方法，例如平均分子量为 39.5 道尔顿的沙眼衣原体主要外膜蛋白。该方法包括以下步骤：向疑似含有细菌抗原的样本中加入缓冲盐溶液，提高所产生的缓冲溶液的 pH 值，孵育溶液，向溶液中加入中和缓冲液以降低 pH 值，用常规免疫测定技术检测样本。可选择在孵育前加热样品溶液，然后在加入中和缓冲液前冷却样品溶液。