10-(2-Bicyclo[2.2.1]hept-5-enyloxy)decane-1-thiol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 10-(2-Bicyclo[2.2.1]hept-5-enyloxy)decane-1-thiol
• 化学式: C₁₇H₃₀OS
• 分子量: 282.5
• InChiKey: JFHQRQNCIYQFDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  19
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  10.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Nanoparticles with Polymer Shells
  申请人：Nanosphere, Inc.

  公开号：EP2000803A1

  公开（公告）日：2008-12-10

  A propagation monomer having the formula P-L-N, wherein: P is a moiety which has redox activity, optical activity, electronic activity, or magnetic activity; N is a cyclic olefin-containing group; L is a bond or linker whereby N is attached to P. The monomers are useful in a method of detecting or quantitating an analyte comprising contacting the analyte with a type of binding monomers having the formula N-L-B wherein: N is a cyclic olefin-containing group; B is a binding moiety that binds specifically to the analyte; and L is a bond or a linker whereby N is attached to B; so that the binding monomers bind to the analyte, and then adding the propagation monomers so that the propagation monomers polymerize to form a polymer attached to the analyte. The properties of the polymer attached to the analyte can be detected or measured in order to detect or quantitate the analyte.

  一种具有式 P-L-N 的传播单体，其中 P 是具有氧化还原活性、光学活性、电子活性或磁性活性的分子； N 是含环烯烃的基团； L 是 N 与 P 连接的键或连接体。 这些单体可用于检测或定量分析物的方法，该方法包括将分析物与具有式 N-L-B 的结合单体接触，其中： N 是含环烯烃的基团； B 是与被分析物特异性结合的结合分子；以及 L 是键或连接剂，N 据此与 B 连接；这样，结合单体就与被分析物结合，然后加入增殖单体，使增殖单体聚合形成附着在被分析物上的聚合物。可以检测或测量附着在被分析物上的聚合物的性质，以检测或量化被分析物。
• Surface and site-specific polymerization by direct-write lithography
  申请人：Mirkin A. Chad

  公开号：US20050272885A1

  公开（公告）日：2005-12-08

  Polymeric microstructures and nanostructures can be prepared with use of a tip to pattern a surface. A tip can be used to pattern a structure which can initiate polymerization. The structure can be then exposed to monomer to induce polymerization at the structure. Alternatively, a tip can be used to pattern a surface with a monomer in which the surface is treated with polymerization catalyst so that polymerization occurs at the patterning site. Ring-opening metathesis polymerization can be carried out with use of the tip to control the polymerization. The tip can be a sharp tip as used in for example an atomic force microscope tip. Norbornene types of monomers can be used. Biological macromolecules can be also prepared.

  聚合物微结构和纳米结构的制备可使用喷嘴对表面进行图案化。喷嘴可用于图案化可引发聚合的结构。然后将该结构暴露在单体中，诱导该结构发生聚合。另外，也可使用喷嘴用单体对表面进行图案化，在图案化部位使用聚合催化剂对表面进行聚合处理。开环偏聚聚合可通过使用喷嘴来控制聚合。针尖可以是尖锐的针尖，例如原子力显微镜的针尖。可以使用降冰片烯类单体。也可以制备生物大分子。
• NANOPARTICLES WITH POLYMER SHELLS
  申请人：Nanosphere, Inc.

  公开号：EP1135682B1

  公开（公告）日：2007-07-11
• EP1135682A4
  申请人：——

  公开号：EP1135682A4

  公开（公告）日：2002-09-25
• SURFACE AND SITE-SPECIFIC POLYMERIZATION BY DIRECT-WRITE LITHOGRAPHY
  申请人：Northwestern University

  公开号：EP1855861A2

  公开（公告）日：2007-11-21