4-[4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]-2-(3,4-dichlorophenyl)-3-oxopentanenitrile

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-[4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]-2-(3,4-dichlorophenyl)-3-oxopentanenitrile
• 化学式: C₂₃H₁₄Cl₃F₃N₂O₃
• 分子量: 529.7
• InChiKey: DAWNQNBXLGTACA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  34
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  72.2
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• Cyanoketone derivative and herbicide containing it as an active component
  申请人：TOKUYAMA CORPORATION

  公开号：EP0506373A2

  公开（公告）日：1992-09-30

  A cyanoketone derivative (I), and a herbicide containing it as an active component. wherein A₁ is a substituted or unsubstituted aromatic group or a substituted or unsubstituted heterocyclic group, each of X₁, X₂ and X₃ is independently an oxygen or sulfur atom, each of B₁, B₂ and B₃ is independently a hydrogen atom or alkyl, each of Y₁, Y₂, Y₃ and Y₄ is independently a hydrogen atom, a halogen atom or alkyl, and A₂ is substituted or unsubstituted alkyl, alkenyl, alkynyl, alkoxy, alkylthio, alkoxycarbonyl, substituted or unsubstituted benzoyl, cyano, a substituted or unsubstituted aromatic group or a substituted or unsubstituted heterocyclic group, provided that when B₁ is a hydrogen atom and B₂ is alkyl, the compound of the formula (1) is any one of two enantiomers with regard to asymmetric carbon to which B₁and B₂ are bonded, or a mixture of these in an arbitrary proportion.

  一种氰酮衍生物（I），以及一种以其为活性成分的除草剂。 其中 A₁ 是取代或未取代的芳香基团或取代或未取代的杂环基团，X₁、X₂ 和 X₃ 中的每一个独立地是氧原子或硫原子，B₁、B₂ 和 B₃ 中的每一个独立地是氢原子或烷基，Y₃ 中的每一个独立地是烷基、各自独立地为氢原子或烷基，Y₁、Y₂、Y₃ 和 Y₄ 各自独立地为氢原子、卤素原子或烷基，A₂ 为取代或未取代的烷基、烯基、炔基、烷氧基、烷硫基、烷基硫代、烷氧基、烷基硫代、烷氧基、烷基硫代、烷基硫代、烷基硫代、烷基硫代、烷基硫代、烷基硫代、烷基硫代烷氧基、烷硫基、烷氧羰基、取代或未取代的苯甲酰基、氰基、取代或未取代的芳香基团或取代或未取代的杂环基团、但当 B₁ 为氢原子、B₂ 为烷基时，式（1）化合物为 B₁ 和 B₂ 所结合的不对称碳的两种对映体中的任意一种，或任意比例的混合物。
• ANTIBACTERIAL AGENT
  申请人：DAIICHI PHARMACEUTICAL CO., LTD.

  公开号：EP0761215A1

  公开（公告）日：1997-03-12

  The present invention provides an antibacterial agent containing, as an active component, a ketonitrile derivative represented by the following formula (1) or a salt thereof: (wherein R1 is a hydrogen atom or lower alkyl, each of R2, R3, R4, and R5, which are identical to or different from one another, is a hydrogen atom, a halogen atom, nitro, lower alkyl, lower alkoxyl, or substituted or unsubstituted phenoxy, X is a substituted or unsubstituted aromatic hydrocarbon group or a substituted or unsubstituted heterocyclic group, and Y is a substituted or unsubstituted aromatic hydrocarbon group, a substituted or unsubstituted heterocyclic group, a carbonyl group substituted by a substituted or unsubstituted aromatic hydrocarbon group or by a substituted or unsubstituted heterocyclic group, or a N,N-di-substituted carbamoyl group). This compound possesses excellent antibacterial activity against both gram-positive and gram-negative bacteria.

  本发明提供了一种抗菌剂，其活性成分含有下式(1)代表的酮腈衍生物或其盐： (其中 R1 是氢原子或低级烷基，R2、R3、R4 和 R5（它们彼此相同或不同）各自是氢原子、卤素原子、硝基、低级烷基、低级烷氧基或取代或未取代的苯氧基，X 是取代或未取代的芳烃基团或取代或未取代的杂环基团、和 Y 是取代或未取代的芳香烃基、取代或未取代的杂环基、被取代或未取代的芳香烃基或取代或未取代的杂环基取代的羰基或 N,N-二取代氨基甲酰基）。这种化合物对革兰氏阳性菌和革兰氏阴性菌都有很好的抗菌活性。
• US5234894A
  申请人：——

  公开号：US5234894A

  公开（公告）日：1993-08-10