1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-二十一氟癸烷-1-磺酸 | 335-77-3

• 物质功能分类: 有机原料 - 有机氟化合物
• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 中文名称: 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-二十一氟癸烷-1-磺酸
• 中文别名: 7-氧杂二环[2.2.1]庚-5-烯-2-羰基氯化；全氟癸烷磺酸钠盐
• 英文名称: perfluorodecanesulfonic acid
• 英文别名: heneicosafluoro-decane-1-sulfonic acid；Heneicosafluor-decan-1-sulfonsaeure；henicosafluorodecanesulfonic acid；Perfluorodecane sulfonic acid；1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-henicosafluorodecane-1-sulfonic acid
• CAS: 335-77-3
• 化学式: C₁₀HF₂₁O₃S
• 分子量: 600.149
• InChiKey: HYWZIAVPBSTISZ-UHFFFAOYSA-N

物化性质

• 密度：
  1.835±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于丙酮（少许）、DMSO（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  35
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  62.8
• 氢给体数：
  1
• 氢受体数：
  24

制备方法与用途

全氟癸烷磺酸钠盐是一种全氟烷基物质（PFAS），常被用作涂层，涂抹于各种日常用品上，以实现防水、防污、阻燃以及持久等效果。

反应信息

• 作为反应物：
  描述：

  1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-二十一氟癸烷-1-磺酸 以 水 为溶剂， 生成 S-benzyl-isothiourea; heneicosafluoro-decane-1-sulfonate
  参考文献：
  名称：

  Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: F: PerFHalOrg.2, 1.3.1, page 76 - 99

  摘要：

  DOI：
• 作为产物：
  描述：

  全氟癸烷磺酰氟 生成 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-二十一氟癸烷-1-磺酸
  参考文献：
  名称：

  Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: F: PerFHalOrg.2, 1.3.1, page 76 - 99

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCING AMINOALKYLSULFONIC ACID AND METHOD OF SALT EXCHANGE FOR SALT THEREOF
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP1548002A1

  公开（公告）日：2005-06-29

  The present invention relates to a method for efficiently producing an aminoalkylsulfonic acid in an industrial scale, and provides    "a process for producing an aminoalkylsulfonic acid represented by the general formula [2]:    wherein R1 and R2 are each independently a hydrogen atom, an alkyl group, an aryl group or an aralkyl group; and R3 and R4 are each independently a hydrogen atom or an alkyl group, comprising reacting an aminoalkylsulfonate salt represented by the general formula [1]:    wherein M is an alkali metal atom, an organic ammonium ion or an ammonium ion; and R1 to R4 are the same as described above,    an aqueous solution thereof, or a solution dissolving any one of them in a water-soluble organic solvent, selected from alcohols having 1 to 3 carbon atoms, carboxylic acids having 2 to 12 carbon atoms and dimethylformamide, with an organic acid; and    a method of salt exchange for an aminoalkylsulfonate salt represented by the general formula [1']:    wherein M' is an alkali metal atom, an organic ammonium ion or an ammonium ion; and R1 and R4 are the same as described above, comprising reacting an aminoalkylsulfonate salt represented by the above general formula [2] with a hydroxide represented by the general formula [6]:         M'OH     [6]    wherein M' is the same as described above, in an alcohol or water".

  本发明涉及一种在工业规模上高效生产氨基磺酸的方法，并提供“一种生产由通式[2]表示的氨基磺酸的方法：其中R1和R2分别是氢原子、烷基、芳基或芳基烷基；R3和R4分别是氢原子或烷基的氨基磺酸盐发生反应所得的方法，通式[1]表示如下：其中M是碱金属原子、有机铵离子或铵离子；R1至R4与上述相同，其水溶液或将任何一种溶解于水溶性有机溶剂中的溶液，所选的有1至3个碳原子的醇、有2至12个碳原子的羧酸和二甲基甲酰胺，与有机酸反应；以及氨基磺酸盐交换的方法，通式[1']表示如下：其中M'是碱金属原子、有机铵离子或铵离子；R1和R4与上述相同，包括将上述通式[2]表示的氨基磺酸盐与通式[6]表示的氢氧化物发生反应：M'OH [6]其中M'与上述相同，在醇或水中”。
• PROCESS FOR PRODUCING ESTER COMPOUND
  申请人：Imazeki Shigeaki

  公开号：US20100324314A1

  公开（公告）日：2010-12-23

  PROBLEM To provide an environmentally-friendly method for producing industrially an ester compound. SOLUTION The present invention is a method for producing an ester compound which comprises subjecting a carboxylic acid and an alcohol to dehydration-condensation reaction using an involatile acid catalyst and then removing the residual acid catalyst by bringing a weak basic substance into contact with the residual acid catalyst.

  问题提供一种生产工业酯化合物的环保方法。 解决方案是一种生产酯化合物的方法，包括将羧酸和醇经过脱水缩合反应，使用一种不挥发的酸催化剂，然后通过将弱碱性物质与残留的酸催化剂接触来去除残留的酸催化剂。
• Silylation of hydroxyl groups
  申请人：——

  公开号：US20030139619A1

  公开（公告）日：2003-07-24

  A compound having a non-silanol hydroxyl group and a compound having a silanol group are subjected to dehydrative condensation in the presence of a compound of formula (1), (2) or (3): MX n (1) Z a SiR 1 b R 2 c R 3 d (2) C m F 2m+1 SO 3 Y   (3) wherein M is a metal, n is the valence of metal M, and X is halogen or C m F 2m+1 SO 3 ; a=1 to 4, b, c and d=0 to 3, a+b+c+d=4, R 1 , R 2 and R 3 are monovalent hydrocarbon groups, Z is halogen or C m F 2m+1 SO 3 ; Y is H or HW, W is an amine NR 4 R 5 R 6 or a nitrogen-containing heterocyclic compound, R 4 , R 5 and R 6 are H or monovalent hydrocarbyl groups, and m=0 to 10. The method is effective in silylating the hydroxyl group without generating a substantial amount of harmful by-products such as hydrogen chloride or triethylamine hydrochloride.

  在化合物1、2或3的存在下，具有非硅醇羟基的化合物和具有硅醇基的化合物进行脱水缩合反应：MXn(1)ZaSiR1bR2cR3d(2)CmF2m+1SO3Y   (3)，其中M为金属，n为金属M的价，X为卤素或CmF2m+1SO3；a=1至4，b、c和d=0至3，a+b+c+d=4，R1、R2和R3为一价烃基，Z为卤素或CmF2m+1SO3；Y为H或HW，W为胺NR4R5R6或含氮杂环化合物，R4、R5和R6为H或一价烃基，m=0至10。该方法可有效硅基化羟基而不产生大量有害副产物，如氢氯酸或三乙胺盐酸盐。
• Galenical formulations
  申请人：Platzek Johannes

  公开号：US20060093554A1

  公开（公告）日：2006-05-04

  This invention describes new galenical formulations that contain paramagnetic and diamagnetic perfluoroalkyl-containing compounds. The new formulations are suitable as contrast media for nuclear spin tomography.

  这项发明描述了包含顺磁和抗磁全氟烷基化合物的新制剂。这些新制剂适用于核磁共振断层扫描作为对比介质。
• Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof
  申请人：Kimura Takuhiro

  公开号：US20050261370A1

  公开（公告）日：2005-11-24

  A process for producing an aminoalkylsulfonic acid of formula [2]: wherein R 1 and R 2 are each independently hydrogen, alkyl, aryl or aralkyl; and R 3 and R 4 are each independently hydrogen or alkyl, comprising reacting an aminoalkylsulfonate salt of formula [1]: wherein M is alkali metal, organic ammonium or ammonium ion; and R 1 to R 4 are as described above, an aqueous solution thereof, or a solution dissolving any one of them in a water-soluble organic solvent, selected from alcohols having 1 to 3 carbon, carboxylic acids having 2 to 12 carbon and dimethylformamide, with an organic acid; and a method of salt exchange for an aminoalkylsulfonate salt of formula [1′]: wherein M′ is alkali metal, organic ammonium or ammonium ion; and R 1 and R 4 are as described above, comprising reacting the aminoalkylsulfonate salt formula [2] with a hydroxide of formula [6]: M′OH  [6] wherein M′ is as described above, in alcohol or water.

  一种生产化学式[2]的氨基烷基磺酸的方法：其中R1和R2各自独立地表示氢、烷基、芳香基或芳基烷基；R3和R4各自独立地表示氢或烷基，包括反应化学式[1]的氨基烷基磺酸盐：其中M为碱金属、有机铵或铵离子；R1至R4如上所述，其水溶性有机溶剂中的水溶性溶液或溶解其中任何一种的溶液，所选的有机酸；以及化学式[1']的氨基烷基磺酸盐的盐交换方法：其中M'为碱金属、有机铵或铵离子；R1和R4如上所述，包括将氨基烷基磺酸盐化学式[2]与化学式[6]的氢氧化物反应：M'OH [6]，其中M'如上所述，在醇或水中。