1,2,3,4,5,6-六-O-甲基-D-山梨糖醇 | 20746-36-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1,2,3,4,5,6-六-O-甲基-D-山梨糖醇
• 英文名称: 1,2,3,4,5,6-hex-O-methyl-D-glucitol
• 英文别名: 1,2,3,4,5-penta-O-methyl-D-glucitol；permethylsorbitol；hexa-O-methyl-D-glucitol；Hexa-O-methyl-D-glucit；Hexa-O-methyl-D-sorbit；Hexa-O-methyl-glucitol；(2R,3R,4R,5S)-1,2,3,4,5,6-hexamethoxyhexane
• CAS: 20746-36-5
• 化学式: C₁₂H₂₆O₆
• 分子量: 266.335
• InChiKey: UJQZVTQJKNAPOQ-WRWGMCAJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  18
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  6

安全信息

• 海关编码：
  2909199090

反应信息

• 作为产物：
  描述：

  山梨醇 生成 1,2,3,4,5,6-六-O-甲基-D-山梨糖醇
  参考文献：
  名称：

  KRUSE, W. M.;STEPHEN, J. F.

  摘要：

  DOI：

文献信息

• Legume saponin of Gleditsia japonica Miquel. II. Desmonoterpenyl glycoside of echinocystic acid.
  作者：TAKAO KONOSHIMA、HIDEO INUI、KEIKO SATO、MARI YONEZAWA、TOKUNOSUKE SAWADA

  DOI：10.1248/cpb.28.3473

  日期：——

  Three triterpenoid saponins were isolated from legumes of Gleditsia japonica cv.'Saponifera'(Leguminosae). These saponins are rare examples of triterpenoid saponins containing monoterpenes. The desmonoterpenyl compound, C74H120O38, [α]23D -42.3°(MeOH), which was obtained from them by alkali hydrolysis with K2CO3, was characterized as a 3, 28-O-bisglycoside on the basis of physical data and degradation products.

  从日本菱角树（Leguminosae）品种"Saponifera"的豆荚中分离出了三种三萜皂苷。这些皂苷是含有单萜的三萜皂苷的稀有例子。通过与K2CO3进行碱性水解，从中获得的去单萜基化合物C74H120O38， [α]23D -42.3°（MeOH），根据物理数据和降解产物的特征，被鉴定为3, 28-O-双糖苷。
• CATIONIC POLYMERS FOR ANTIMICROBIAL APPLICATIONS AND DELIVERY OF BIOACTIVE MATERIALS
  申请人：AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

  公开号：US20140220093A1

  公开（公告）日：2014-08-07

  A cationic star polymer is disclosed of the general formula (1): wherein w′ is a positive number greater than or equal to 3, I′ is a dendritic polyester core covalently linked to w′ independent peripheral linear cationic polymer chains P′. Each of the chains P′ comprises a cationic repeat unit comprising i) a backbone functional group selected from the group consisting of aliphatic carbonates, aliphatic esters, aliphatic carbamates, aliphatic ureas, aliphatic thiocarbamates, aliphatic dithiocarbonates, and combinations thereof, and ii) a side chain comprising a quaternary amine group. The quaternary amine group comprises a divalent methylene group directly covalently linked to i) a positive charged nitrogen and ii) an aromatic ring.

  本发明揭示了一种阳离子星形聚合物，其一般式为(1)：其中w'是大于或等于3的正数，I'是与w'个独立的外周线性阳离子聚合物链P'共价连接的树状聚酯核心。每个链P'包含一个阳离子重复单元，包括：i）选择自脂肪族碳酸酯、脂肪族酯、脂肪族氨基甲酸酯、脂肪族脲、脂肪族硫代氨基甲酸酯、脂肪族二硫代碳酸酯和其组合的骨架功能基；以及ii）包含季铵基的侧链。季铵基包括一个直接共价连接到i）一个带正电的氮和ii）一个芳香环的二价亚甲基基团。
• The Chemistry of Naturally Occurring Monoanhydrohexitols. II. Synthetic Tetramethylstyracitol¹
  作者：Werner Freudenberg、John T. Sheehan

  DOI：10.1021/ja01860a032

  日期：1940.3
• Araki; Hashi, Nippon Kagaku Kaishi/Journal of the Chemical Society of Japan, 1940, vol. 61, p. 101,103
  作者：Araki、Hashi

  DOI：——

  日期：——
• Niacin Mimetics, and Methods of Use Thereof
  申请人：Arisaph Pharmaceuticals

  公开号：US20140018359A1

  公开（公告）日：2014-01-16

  Disclosed are 6-(morpholinoalkyl)-substituted pyridines, and pharmaceutically acceptable salts and prodrugs thereof, that are active against a range of mammalian therapeutic indications.