1,4-二(十八烷基)磺酸基琥珀酸钠 | 10027-28-8

• 物质功能分类: 化学试剂 - 有机试剂
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 1,4-二(十八烷基)磺酸基琥珀酸钠
• 英文名称: Sodium 1,4-dioctadecyl sulphonatosuccinate
• 英文别名: sodium;1,4-dioctadecoxy-1,4-dioxobutane-2-sulfonate
• CAS: 10027-28-8
• 化学式: C40H77NaO7S
• 分子量: 725.1
• InChiKey: MNUUUYJEIIJTKT-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  8.9
• 重原子数：
  49
• 可旋转键数：
  39
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  118
• 氢给体数：
  0
• 氢受体数：
  7

安全信息

• 海关编码：
  2914509090

文献信息

• Particulate construct comprising polyhydroxyalkanoate and method for producing it
  申请人：——

  公开号：US20030194443A1

  公开（公告）日：2003-10-16

  The invention provides a particulate construct such as microcapsules containing a drug, and serving a slow releasing preparation not associated with a practically unacceptable initial burst release but showing a practically acceptable zero-order release for a certain period and a producing method for such particulate construct, and a slow releasing preparation of a high drug content capable of stably incorporating the drug in the particulate construct such as microcapsules, and a producing method for such preparation. The invention also provides a particulate construct such as microcapsules utilizing a highly functional polymer compound and incorporating oil phase and/or water phase in solid phase, and a producing method therefor. Furthermore, the invention provides a particulate construct such as microcapsules having a hollow structure of a single polymer membrane as the outer shell and capable of containing many bubbles in the fine particles, and a producing method capable of preparing such construct with a high reproducibility. According to the invention, a particulate construct such as microcapsules is formed with polyhydroxyalkanoate of a specified structure and a drug for a desired purpose, an oil phase and/or a water phase, or a gaseous phase is included in such construct.

  本发明提供了一种微粒构造物，例如包含药物的微胶囊，用作缓释制剂，不会出现实际上不可接受的初始爆发释放，但在一定时间内显示实际上可接受的零级释放，并提供了这种微粒构造物的制备方法，以及能够稳定地将药物纳入微粒构造物中，例如微胶囊的高药物含量的缓释制剂，以及这种制备方法。本发明还提供了一种利用高功能聚合物化合物并将油相和/或水相纳入固相的微粒构造物，以及其制备方法。此外，本发明还提供了一种具有单一聚合物膜的空心结构的微粒构造物，能够在细小的颗粒中包含许多气泡，并提供了一种能够高度重复制备这种构造物的制备方法。根据本发明，可使用具有特定结构的聚羟基烷酸酯和药物制备微粒构造物，该构造物中包含油相和/或水相或气态相。
• Coloring composition for color filters containing microencapsulated pigment composed of polyhydroxyalkanoate
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20030203458A1

  公开（公告）日：2003-10-30

  The invention provides coloring composition for color filters making use of a pigment, in which the dispersed state of the pigment is stable without using any surfactant, and so aggregation is hard to occur, and which permits formation of high-definition and high-quality images excellent in color rendition, transparency and contrast, and a simple production process thereof, by which the use of surfactants can be abolished, or the amount of surfactants used can be reduced to a great extent. The coloring composition for color filters is provided by using at least a coloring material obtained by coating at least part of surfaces of pigment particles with polyhydroxyalkanoate, and a dispersion medium for the coloring material.

  该发明提供了一种用于彩色滤光片的染色组合物，其中颜料的分散状态稳定，不需要使用任何表面活性剂，因此聚集很难发生，并且允许形成高清晰度和高质量的图像，具有出色的色彩再现度、透明度和对比度，以及简单的生产过程，通过该过程可以废除表面活性剂的使用，或者大大减少所使用的表面活性剂的数量。通过使用至少一种染色材料，该染色材料通过在颜料颗粒的至少一部分表面上涂覆聚羟基烷酸酯而获得，并且用于染色材料的分散介质。
• Polyhydroxyalkanoate-containing magnetic structure, and manufacturing method and use thereof
  申请人：Yano Tetsuya

  公开号：US20060263432A1

  公开（公告）日：2006-11-23

  A structure containing polyhydroxyalkanoate and a magnetic substance includes an external phase part containing polyhydroxyalkanoate and an internal phase part contained in the external phase part, at least one of the external phase part and the internal phase part containing a magnetic substance. Accordingly, provided is a microcapsule, which can be suitably used for formation of an active ingredient of a sustained release pharmaceutical preparation or an ultrasonic contrast agent.

  一种含有聚羟基脂肪酸酯和磁性物质的结构，包括一个包含聚羟基脂肪酸酯的外相部分和一个包含在外相部分中的内相部分，其中至少一个外相部分和内相部分含有磁性物质。因此，提供了一种微胶囊，可适用于制备持续释放药物制剂或超声造影剂的活性成分。
• Coloring composition containing a pigment coated by a polyhydroxyalkanoate
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP1262229A1

  公开（公告）日：2002-12-04

  The invention provides coloring composition for color filters making use of a pigment, in which the dispersed state of the pigment is stable without using any surfactant, and so aggregation is hard to occur, and which permits formation of high-definition and high-quality images excellent in color rendition, transparency and contrast, and a simple production process thereof, by which the use of surfactants can be abolished, or the amount of surfactants used can be reduced to a great extent. The coloring composition for color filters is provided by using at least a coloring material obtained by coating at least part of surfaces of pigment particles with polyhydroxyalkanoate, and a dispersion medium for the coloring material.

  本发明提供了使用颜料的彩色滤光片用着色组合物，在该组合物中，颜料的分散状态稳定，无需使用任何表面活性剂，因此不易发生聚集，可形成色彩还原性、透明度和对比度极佳的高清晰度和高质量图像，而且其生产工艺简单，可以不使用表面活性剂，或大大减少表面活性剂的用量。该彩色滤光片的着色组合物至少使用了一种通过在颜料颗粒的至少部分表面涂覆聚羟基烷酸酯而获得的着色材料，以及一种用于该着色材料的分散介质。
• AMADORIASE HAVING IMPROVED ANIONIC-SURFACTANT RESISTANCE
  申请人：Kikkoman Corporation

  公开号：EP3216865A1

  公开（公告）日：2017-09-13

  The present invention provides a composition that enables measurement of glycated hemoglobin in the presence of a stronger surfactant than conventional surfactants. To this end, the present invention provides an amadoriase in which one or more amino acids have been substituted at positions corresponding to positions selected from the group consisting of positions 80, 71, 175, 172, 279, 12, 9, 77, 30, 28, 13, 3, 4, 286, 204, 338, 44, 340, and 194 of the amadoriase derived from the genus Coniochaeta having the amino acid sequence as shown in SEQ ID NO: 1 as well as a composition for measurement of glycated hemoglobin comprising an amadoriase that retains activity in the presence of an anionic surfactant. The present invention can provide an enzyme and a composition for measurement of glycated hemoglobin that sufficiently remain stable even when exposed to anionic surfactants.

  本发明提供了一种组合物，该组合物能够在比传统表面活性剂更强的表面活性剂存在下测量糖化血红蛋白。为此，本发明提供了一种氨甲蝶呤酶，其中一个或多个氨基酸在与选自具有 SEQ ID NO：1 所示氨基酸序列的氨甲蝶呤酶，以及一种用于测量糖化血红蛋白的组合物，该组合物包含一种在阴离子表面活性剂存在下仍能保持活性的氨甲蝶呤酶。本发明可提供一种用于测量糖化血红蛋白的酶和组合物，即使暴露于阴离子表面活性剂中也能充分保持稳定。