methyl (19E,21E,23E,25E,27E,29E,31E)-33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl (19E,21E,23E,25E,27E,29E,31E)-33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate
• 化学式: C₄₈H₇₅NO₁₇
• 分子量: 938.1
• InChiKey: UAZIZEMIKKIBCA-QQNUUWEYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  66
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  309
• 氢给体数：
  11
• 氢受体数：
  18

文献信息

• Antifungal and Antiparasitic Polyene Macrolides
  申请人：Tunac Josefino B.

  公开号：US20130123205A1

  公开（公告）日：2013-05-16

  In certain aspects, the present disclosure provides for novel, water-soluble polyene macrolides and salts or solvates thereof and methods of making the water-soluble polyene macrolides. Also provided are compositions and methods for inhibiting, preventing, and/or treating fungal and parasitic diseases in a subject.
• ANTIFUNGAL AND ANTIPARASITIC POLYENE MACROLIDES
  申请人：ACEA Biotech, Inc.

  公开号：US20160129026A1

  公开（公告）日：2016-05-12

  In certain aspects, the present disclosure provides for novel, water-soluble polyene macrolides and salts or solvates thereof and methods of making the water-soluble polyene macrolides. Also provided are compositions and methods for inhibiting, preventing, and/or treating fungal and parasitic diseases in a subject.
• US9212201B2
  申请人：——

  公开号：US9212201B2

  公开（公告）日：2015-12-15